Hepatoblastoma
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Hepatoblastoma Overview

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What is the definition of Hepatoblastoma?
Hepatoblastoma is a rare malignant (cancerous) tumor of the live, usually affecting young children. In early stages of the condition, there may be no concerning signs or symptoms. As the tumor gets larger, affected children may experience a painful, abdominal lump; swelling of the abdomen; unexplained weight loss; loss of appetite; and/or nausea and vomiting. The exact underlying cause of Hepatoblastoma is poorly understood. Risk factors for the tumor include prematurity with a very low birth weight, early exposure to hepatitis B infection, biliary atresia, and several different genetic conditions (i.e. Beckwith-Wiedemann syndrome, familial adenomatous polyposis, Aicardi syndrome, Glycogen storage disease, and Simpson-Golabi-Behmel syndrome).
What are the alternative names for Hepatoblastoma?
  • Hepatoblastoma
Who are the top Hepatoblastoma Local Doctors?
Elite in Hepatoblastoma
Dr. Rakesh Sindhi
General Surgery
Elite in Hepatoblastoma
Dr. Rakesh Sindhi
General Surgery
Referral may be required

UPMC Children's Hospital Of Pittsburgh, Pediatric Transplant Services

4401 Penn Avenue, 
Pittsburgh, PA 
412-530-6840
Languages Spoken:
English, Hindi
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Accepting New Patients
Offers Telehealth

Rakesh Sindhi, MD, FACS, is a pediatric abdominal transplant surgeon, board-certified in surgery by the American Board of Surgery. He is co-director of Pediatric Transplantation, director of Pediatric Transplant Research, and professor of surgery at the University of Pittsburgh School of Medicine. Dr. Sindhi is rated as an Elite provider by MediFind in the treatment of Hepatoblastoma. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Hepatoblastoma, Biliary Atresia, Liver Failure, Liver Transplant, and Small Bowel Resection. Dr. Sindhi is board certified in American Board Of Surgery. Dr. Sindhi is currently accepting new patients.

Advanced in Hepatoblastoma
Dr. Joel A. Kaplan
Pediatrics | Hematology | Oncology
Advanced in Hepatoblastoma
Dr. Joel A. Kaplan
Pediatrics | Hematology | Oncology
Referral may be required

Atrium Health Levine Children’s Cancer & Blood Disorders, A Facility Of Carolinas Medical Center

1001 Blythe Blvd., Suite 3000, 
Charlotte, NC 
704-381-9900
Experience:
25+ years
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Joel Kaplan is a Hematologist and a Pediatrics provider practicing medicine in Charlotte, North Carolina. He has been practicing medicine for over 25 years. Dr. Kaplan is rated as an Advanced provider by MediFind in the treatment of Hepatoblastoma. He is also highly rated in 15 other conditions, according to our data. His clinical expertise encompasses Neuroblastoma, Embryonal Tumor with Multilayered Rosettes, Medulloblastoma, Langerhans Cell Histiocytosis, and Bone Marrow Aspiration. Dr. Kaplan is board certified in American Board Of Pediatrics and American Board Of Pediatrics, Pediatric Hematology And Oncology. Dr. Kaplan is currently accepting new patients.

 
 
 
 
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Elite in Hepatoblastoma
Eiso Hiyama
Elite in Hepatoblastoma
Eiso Hiyama
Referral may be required
Hiroshima, JP 

Eiso Hiyama practices practicing medicine in Hiroshima, Japan. Hiyama is rated as an Elite expert by MediFind in the treatment of Hepatoblastoma. They are also highly rated in 5 other conditions, according to our data. Their clinical expertise encompasses Hepatoblastoma, Neuroblastoma, Liver Cancer, Pancreaticoduodenectomy, and Hepatectomy.

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What are the latest Hepatoblastoma Clinical Trials?
A Randomized Phase I/II Study of Talazoparib or Temozolomide in Combination With Onivyde in Children With Recurrent Solid Malignancies and Ewing Sarcoma
A Randomized Phase I/II Study of Talazoparib or Temozolomide in Combination With Onivyde in Children With Recurrent Solid Malignancies and Ewing Sarcoma
Who is this study for: Children with recurrent solid malignancies and Ewing sarcoma
Enrollment Status: Recruiting
Publish Date: May 19, 2026
Intervention Type: Drug
Study Drugs: Onivyde, Talazoparib, Temozolomide
Study Phase: Phase 1/Phase 2

Summary: The phase I portion of this study is designed for children or adolescents and young adults (AYA) with a diagnosis of a solid tumor that has recurred (come back after treatment) or is refractory (never completely went away). The trial will test 2 combinations of therapy and participants will be randomly assigned to either Arm A or Arm B. The purpose of the phase I study is to determine the highest ...

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B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
Who is this study for: Patients with Solid Tumors
Enrollment Status: Recruiting
Publish Date: May 19, 2026
Intervention Type: Drug
Study Drugs: Fludarabine, Cyclophosphamide, MESNA, B7-H3 CAR T cells
Study Phase: Phase 1

Summary: 3CAR is being done to investigate an immunotherapy for patients with solid tumors. It is a Phase I clinical trial evaluating the use of autologous T cells genetically engineered to express B7-H3-CARs for patients ≤ 21 years old, with relapsed/refractory B7-H3+ solid tumors. This study will evaluate the safety and maximum tolerated dose of B7-H3-CAR T cells.The purpose of this study is to find the ...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center