Learn About Hereditary Pancreatitis

What is the definition of Hereditary Pancreatitis?

Hereditary pancreatitis is a genetic condition characterized by recurrent episodes of inflammation of the pancreas (pancreatitis). The pancreas produces enzymes that help digest food, and it also produces insulin, a hormone that controls blood sugar levels in the body. Episodes of pancreatitis can lead to permanent tissue damage and loss of pancreatic function.

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What are the causes of Hereditary Pancreatitis?

Mutations in the PRSS1 gene cause most cases of hereditary pancreatitis. The PRSS1 gene provides instructions for making an enzyme called cationic trypsinogen. This enzyme is produced in the pancreas and helps with the digestion of food. When cationic trypsinogen is needed, it is released (secreted) from the pancreas and transported to the small intestine, where it is cut (cleaved) into its working or active form called trypsin. When digestion is complete and trypsin is no longer needed, the enzyme is broken down.

How prevalent is Hereditary Pancreatitis?

Hereditary pancreatitis is thought to be a rare condition. In Europe, its prevalence is estimated to be 3 to 6 per million individuals.

Is Hereditary Pancreatitis an inherited disorder?

When hereditary pancreatitis is caused by mutations in the PRSS1 gene, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In some cases, an affected person inherits the PRSS1 gene mutation from one affected parent. Other cases result from new mutations in the gene and occur in people with no history of the disorder in their family.

Who are the top Hereditary Pancreatitis Local Doctors?
Elite
Highly rated in
28
conditions
Gastroenterology

Orlando Health Digestive Health Institute

52 W Underwood St 
Orlando, FL 

Shyam Varadarajulu is a Gastroenterologist in Orlando, Florida. Varadarajulu has been practicing medicine for over 29 years and is rated as an Elite expert by MediFind in the treatment of Hereditary Pancreatitis. He is also highly rated in 28 other conditions, according to our data. His top areas of expertise are Pancreatic Pseudocyst, Hereditary Pancreatitis, Acute Pancreatitis, and Jaundice. He is licensed to treat patients in Florida. Varadarajulu is currently accepting new patients.

Elite
Highly rated in
23
conditions
Gastroenterology
Student
Internal Medicine

Ashley River Tower

25 Courtenay Dr 
Charleston, SC 

Badih Joseph is a Gastroenterologist and a Student in Charleston, South Carolina. Joseph is rated as an Elite expert by MediFind in the treatment of Hereditary Pancreatitis. He is also highly rated in 23 other conditions, according to our data. His top areas of expertise are Acute Pancreatitis, Hereditary Pancreatitis, Choledocholithiasis, and Chronic Pancreatitis. He is licensed to treat patients in Michigan and South Carolina. Joseph is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
9
conditions
Gastroenterology

Stanford Health Care

Stanford Health Care

300 Pasteur Dr # Mc5187 
Stanford, CA 

Walter Park is a Gastroenterologist in Stanford, California. Park has been practicing medicine for over 19 years and is rated as an Elite expert by MediFind in the treatment of Hereditary Pancreatitis. He is also highly rated in 9 other conditions, according to our data. His top areas of expertise are Hereditary Pancreatitis, Chronic Pancreatitis, Acute Pancreatitis, and Childhood Pancreatitis. He is licensed to treat patients in California. Park is currently accepting new patients.

What are the latest Hereditary Pancreatitis Clinical Trials?
Effect of Non-enteric Coated Enzymes Substitution on Pain in Patients With Chronic Pancreatitis: a Double -Blinded Placebo Controlled Randomized Trial (NE-PERT Trial)
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Establishment and Verification of Pancreatic Volume Formula Based on Imaging: A Cross-sectional Study
Who are the sources who wrote this article ?

Published Date: October 01, 2012Published By: National Institutes of Health

What are the Latest Advances for Hereditary Pancreatitis?
10-Year Comparative Follow-up of Familial versus Multifactorial Chylomicronemia Syndromes.
Pediatric Intracranial Hypertension: A Spotlight on Imaging, the Idiopathic Intracranial Hypertension Treatment Trial, and COVID-19 Associated Cases.
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Deleterious Effects of SARS-CoV-2 Infection on Human Pancreatic Cells.