Learn About Hereditary Spastic Paraparesis

What is the definition of Hereditary Spastic Paraparesis?
Hereditary spastic paraparesis is a term that refers to a group of genetic degenerative neurological disorders that affect the upper motor neurons, causing progressive weakness and spasticity of the legs. There are more than 80 different types of hereditary spastic paraparesis.
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What are the symptoms of Hereditary Spastic Paraparesis?
Hereditary spastic paraparesis can be uncomplicated, complicated, or complex. Symptoms of hereditary spastic paraparesis depend on the subtype and usually appear in early childhood. Symptoms of hereditary spastic paraparesis include muscle weakness and spasticity in the legs; difficulty walking; toe drag; impaired vision; balance problems; seizures; cognitive impairment; peripheral neuropathy; deafness; knee, hip, back, and ankle pain; urinary urgency; difficulty swallowing; and speech difficulties.
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What are the current treatments for Hereditary Spastic Paraparesis?
Treatment for hereditary spastic paraparesis depends on the subtype and symptoms. Treatment for hereditary spastic paraparesis may include watchful waiting; exercise; physical therapy; muscle-relaxing medications, such as Lioresal, baclofen, or botulinum toxin; oxybutynin; and orthotics.
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What are the Latest Advances for Hereditary Spastic Paraparesis?
Management of rare movement disorders in Europe: outcome of surveys of the European Reference Network for Rare Neurological Diseases.
Improvement in overactive bladder symptoms in patients using functional electrical stimulation of the common peroneal nerve for walking.
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