Respiratory Muscles and Work of Breathing in Children

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Respiratory muscle testing allows a quantitative assessment of inspiratory and expiratory muscles in children of any age with primary or secondary respiratory muscle impairment, in order to better understand the pathophysiology of respiratory impairment and guide therapeutic management. The use of an invasive technique (esogastric probe) makes it possible to specifically explore the diaphragm, the accessory inspiratory muscles and the expiratory muscles in order to detect dysfunction or paralysis of these muscles, and to estimate the work of breathing in order to better guide the respiratory management. The primary objective of the study is to evaluate the respiratory effort in children with primary or secondary impairment of the respiratory muscles during spontaneous breathing or during mechanical ventilation.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 17
Healthy Volunteers: f
View:

• Patients aged less than 18 years old with primary or secondary impairment of respiratory muscles and followed at Necker Hospital

• Patients under spontaneous breathing or noninvasive or invasive mechanical ventilation

• Written informed consent

Locations
Other Locations
France
Hôpital Necker-Enfants Malades
RECRUITING
Paris
Contact Information
Primary
Brigitte FAUROUX, MD, PhD
brigitte.fauroux@aphp.fr
1 71 19 60 92
Backup
Hélène MOREL
helene.morel@aphp.fr
1 71 19 63 46
Time Frame
Start Date: 2022-01-19
Estimated Completion Date: 2028-01
Participants
Target number of participants: 550
Treatments
Experimental: Respiratory muscle impairment
Minor patients with primary or secondary impairment of respiratory muscles and followed at Necker Hospital
Sponsors
Collaborators: URC-CIC Paris Descartes Necker Cochin
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov