Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.
Locations
United States
California
University of California, Los Angeles
RECRUITING
Los Angeles
Contact Information
Primary
Daniel Lu, MD
dclu@mednet.ucla.edu
310/825/4321
Time Frame
Start Date: 2011-01-21
Estimated Completion Date: 2027-01-22
Participants
Target number of participants: 150
Treatments
Experimental: Electrical Stimulation group
Epidural Electrical Stimulation of the Cervical Spinal Cord
Related Therapeutic Areas
Sponsors
Leads: University of California, Los Angeles