Cholesterol is a fat (also called a lipid) that your body needs to work properly. Too much bad cholesterol can increase your chance of getting heart disease, stroke, and other problems.
The medical term for high blood cholesterol is lipid disorder, hyperlipidemia, or hypercholesterolemia.
Cholesterol - high; Lipid disorders; Hyperlipoproteinemia; Hyperlipidemia; Dyslipidemia; Hypercholesterolemia
Common conditions include: Familial Hypercholesterolemia
There are many types of cholesterol. The ones talked about most are:
For many people, abnormal cholesterol levels are partly due to an unhealthy lifestyle. This often includes eating a diet that is high in fat. Other lifestyle factors are:
Some health conditions can also lead to abnormal cholesterol, including:
Medicines such as certain birth control pills, diuretics (water pills), beta-blockers, and some medicines used to treat depression may also raise cholesterol levels. Several disorders that are passed down through families lead to abnormal cholesterol and triglyceride levels. They include:
Smoking does not cause higher cholesterol levels, but it can reduce your HDL (good) cholesterol.
Steps you can take to improve your cholesterol levels and to help prevent heart disease and a heart attack include:
Your provider may want you to take medicine for your cholesterol if lifestyle changes do not work. This will depend on:
You are more likely to need medicine to lower your cholesterol:
Almost everyone else may get health benefits from LDL cholesterol that is lower than 160 to 190 mg/dL.
There are several types of drugs to help lower blood cholesterol levels. The drugs work in different ways. Statins are one kind of drug that lowers cholesterol and has been proven to reduce the chance of heart disease. Other drugs are available if your risk is high and statins do not lower your cholesterol levels enough. These include ezetimibe and PCSK9 inhibitors.
High cholesterol levels can lead to hardening of the arteries, also called atherosclerosis. This occurs when fat, cholesterol, and other substances build up in the walls of arteries and form hard structures called plaques.
Over time, these plaques can block the arteries and cause heart disease, stroke, and other symptoms or problems throughout the body.
Disorders that are passed down through families often lead to higher cholesterol levels that are harder to control.
Published Date: February 23, 2022
Published By: Thomas S. Metkus, MD, Assistant Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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