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The Impact of Almond Size in a White Chocolate Matrix on Satiation, Postprandial Glycemia & Lipemia, Chewing Exertion, Eating Rate, and Product Liking: A Randomized Crossover Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are: * Does the presence or preparation of almonds (whole versus chopped) influence satiation, i.e., the amount consumed at an ad libitum meal? * What is the correlation between chewing behaviour, satiation, and changes in postprandial glucose, triacylglycerols, and satiety ratings? Participants will attend the research centre fasted on three occasions to consume an ad libitum meal, complete questionnaires, and provide fasting and postprandial finger prick blood samples.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:

• BMI between 18.5-27.9 kg/m\^2 or waist circumference less than 88 cm

• No known food allergies or sensitivities

• Non-restrained eaters based on the Three Factor Eating Questionnaire

• No history of gastrointestinal diseases that may interfere with eating behaviour or digestion

• Not on medications that affect appetite, digestion, blood sugar regulation, saliva production, or chewing

• Stable medication use

• Non-smokers

• Not gained or lost significant weight during the past 3 months

• Regular monthly menstrual cycles

• Not pregnant, lactating, or post-menopausal

Locations
Other Locations
Canada
Department of Human Health Sciences
RECRUITING
Guelph
Contact Information
Primary
Amanda J Wright, PhD
ajwright@uoguelph.ca
519-824-4120
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2026-05
Participants
Target number of participants: 35
Treatments
Experimental: White chocolate with whole almonds
Ad libitum serving with 2.25:1 weight per cent chocolate:almonds
Experimental: White chocolate without almonds
Ad libitum serving
Experimental: White chocolate with chopped almonds
Ad libitum serving with 2.25:1 weight per cent chocolate:almonds
Related Therapeutic Areas
Sponsors
Leads: University of Guelph

This content was sourced from clinicaltrials.gov