Hirschsprung DiseaseSymptoms, Doctors, Treatments, Advances & More
Learn About Hirschsprung Disease
Hirschsprung disease is an intestinal disorder characterized by the absence of nerves in parts of the intestine. This condition occurs when the nerves in the intestine (enteric nerves) do not form properly during development before birth (embryonic development). This condition is usually identified in the first two months of life, although less severe cases may be diagnosed later in childhood.
Isolated Hirschsprung disease can result from mutations in one of several genes, including the RET, EDNRB, and EDN3 genes. However, the genetics of this condition appear complex and are not completely understood. While a mutation in a single gene sometimes causes the condition, mutations in multiple genes may be required in some cases. The genetic cause of the condition is unknown in approximately half of affected individuals.
Hirschsprung disease occurs in approximately 1 in 5,000 newborns.
Approximately 20 percent of cases of Hirschsprung disease occur in multiple members of the same family. The remainder of cases occur in people with no history of the disorder in their families.
UC Irvine Medical Center
Dr. Hira Ahmad is a board-certified UCI Health pediatric surgeon.She earned her medical degree at Creighton University School of Medicine in Omaha, Neb. She completed a residency in general surgery at the Cleveland Clinic in Weston, Fla., followed by a fellowship in pediatric colorectal surgery at Nationwide Children's Hospital in Columbus, Ohio. Next, she completed a fellowship in pediatric surgery at the University of Washington School of Medicine in Seattle.Ahmad sees patients inOrange. Dr. Ahmad is rated as an Elite provider by MediFind in the treatment of Hirschsprung Disease. She is also highly rated in 22 other conditions, according to our data. Her clinical expertise encompasses Hirschsprung Disease, Imperforate Anus, Total Intestinal Aganglionosis, Colostomy, and Bladder Reconstruction. Dr. Ahmad is board certified in American Board Of Surgery - Pediatric Surgery.
Main Hospital-Surgical Specialty Clinic
Marc Levitt is a General Surgeon practicing medicine in Washington, Washington, D.c.. He has been practicing medicine for over 33 years. Dr. Levitt is rated as an Elite provider by MediFind in the treatment of Hirschsprung Disease. He is also highly rated in 13 other conditions, according to our data. His clinical expertise encompasses Hirschsprung Disease, Total Intestinal Aganglionosis, Bowel Incontinence, Colostomy, and Ileostomy. Dr. Levitt is board certified in Pediatric Surgery: American Board Of Surgery, 2012, Surgery (General Surgery): American Board Of Surgery, 2010, and Cardiothoracic Surgery: American Board Of Surgery, 2010.
Atrium Health Levine Children's Gastroenterology
Jason Dranove is a Pediatric Gastroenterologist and a Hepatologist practicing medicine in Charlotte, North Carolina. Dr. Dranove is rated as an Advanced provider by MediFind in the treatment of Hirschsprung Disease. He is also highly rated in 2 other conditions, according to our data. His clinical expertise encompasses Hirschsprung Disease, Neurogenic Bowel, Total Intestinal Aganglionosis, and Bowel Incontinence. Dr. Dranove is board certified in American Board Of Pediatrics. Dr. Dranove is currently accepting new patients.
Summary: Hirschsprung disease is a genetic condition caused by lack of nerve cells in varying lengths of the intestines. This study will investigate the complex genetic basis of the disease, which involves multiple interacting genetic factors.
Summary: This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.
Published Date: May 01, 2018
Published By: National Institutes of Health