Stimulation Modeling and Adaptive Response Tracking in Pediatric Gastrointestinal Motility Disorders
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders. By combining advanced neuroimaging, patient-specific biophysical modeling, electrophysiological characterization, and clinical translation, the SMART-GUT project establishes a comprehensive framework to systematically investigate neuromodulation in this pediatric population. This integrative approach enables a direct link between mechanism, targeting, and clinical outcome.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 18
Healthy Volunteers: f
View:
• informed consent of patient and care taker
• gastrointestinal motility disorder, disregarding underlying diseases
• exclusion of mechanical obstructions in the gastrointestinal passage
• age between 3 and 18
Locations
Other Locations
Germany
Pediatric Surgery in the Children's Hospital
RECRUITING
Erlangen
Contact Information
Primary
Sonja Diez, PD Dr. med.
sonja.diez@uk-erlangen.de
09131 - 85 32923
Time Frame
Start Date: 2018-07-01
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 25
Treatments
Active_comparator: SNM-guided implantation
Surgical implantation of sacral neuromodulation after generation of digital twin and intraoperative efficacy testing
No_intervention: SNM
SNM implantation based on general knowledge and adult measurements
Related Therapeutic Areas
Sponsors
Leads: Friedrich-Alexander-Universität Erlangen-Nürnberg