Latest Advances

  • Condition: Epstein-Barr Virus-Related Hemophagocytic Lymphohistiocytosis
  • Journal: Medicine
  • Treatment Used: Ruxolitinib with the HLH-94 Protocol
  • Number of Patients: 1
  • Published —
This study presents a case of a critically ill 14-year-old girl with Epstein-Barr virus-related hemophagocytic lymphohistiocytosis who was treated with Ruxolitinib in conjunction with the HLH-94 protocol.
  • Condition: Niemann-Pick Disease (NPD)
  • Journal: Orphanet journal of rare diseases
  • Treatment Used: Enzyme Replacement Therapy (ERT) with Olipudase Alfa
  • Number of Patients: 5
  • Published —
This study assessed the effect of enzyme replacement therapy (ERT) in patients with Niemann-Pick disease (enzyme disorder; NPD).
  • Condition: Subcutaneous Panniculitis-Like T-Cell Lymphoma with Hemophagocytic Lymphohistiocytosis Mimicking Cellulitis
  • Journal: The American journal of case reports
  • Treatment Used: Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone, and Etoposide (ECHOP) Chemotherapy
  • Number of Patients: 1
  • Published —
This case report describes a patient with a rare form of subcutaneous panniculitis-like T-cell lymphoma with hemophagocytic lymphohistiocytosis that mimicked cellulitis.
  • Condition: Erdheim-Chester Disease (ECD)
  • Journal: The Canadian journal of urology
  • Treatment Used: Percutaneous Nephrolithotomy
  • Number of Patients: 1
  • Published —
This case report describes a patient with Erdheim-Chester disease (ECD), a rare systemic disorder, who developed kidney stones treated with percutaneous nephrolithotomy.
  • Condition: Refractory Adult-Onset Still's Disease with Macrophage Activation Syndrome
  • Journal: Modern rheumatology case reports
  • Treatment Used: Tocilizumab
  • Number of Patients: 1
  • Published —
The study researched the use of Tocilizumab for refractory adult-onset still's disease with macrophage activation syndrome.
  • Condition: COVID-19
  • Journal: Frontiers in medicine
  • Treatment Used: Ruxolitinib
  • Number of Patients: 18
  • Published —
In this study, researchers evaluated the safety and effectiveness of ruxolitinib for the treatment of COVID-19.
  • Condition: Patients with Cytokine Storm Syndrome (CSS) induced by SARS-CoV-2 Infection
  • Journal: Medicina clinica (English ed.)
  • Treatment Used: Corticoid Pulses
  • Number of Patients: 92
  • Published —
This study evaluated the effectiveness of glucocorticoids (GCs) for the treatment of cytokine storm syndrome (CSS) in patients with COVID-19.
  • Condition: Hemophagocytic Lymphohistiocytosis (HLH) caused by COVID-19
  • Journal: Clinical infection in practice
  • Treatment Used: Anakinra
  • Number of Patients: 1
  • Published —
The study researched the use of Anakinra in a patients with hemophagocytic lymphohistiocytosis (HLH) caused by COVID-19 infection.
  • Condition: SARS CoV 2 Infection in Chronic Myelogenous Leukemia
  • Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
  • Treatment Used: Immunoglobulin, Steroids, and Antiviral Therapy
  • Number of Patients: 1
  • Published —
This case report describes a patient with COVID-19 and chronic myelogenous leukemia treated with intravenous immunoglobulin, steroids, and antiviral therapy.
  • Condition: Scapular Langerhans Cell Histiocytosis
  • Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • Treatment Used: CT-Guided Corticosteroid Injection
  • Number of Patients: 1
  • Published —
The study researched the use of CT-guided corticosteroid injection for a patient with scapular langerhans cell histiocytosis.
  • Condition: COVID-19
  • Journal: Journal of cellular physiology
  • Treatment Used: Interleukin (IL)-18 Targeted Therapies
  • Number of Patients: 0
  • Published —
This article discusses the potential for interleukin (IL)-18 targeted therapies in the treatment of COVID-19.
  • Condition: Pediatric Primary Hemophagocytic Lymphohistiocytosis
  • Journal: Annals of hematology
  • Treatment Used: HLH-94/2004
  • Number of Patients: 38
  • Published —
This study tested the safety and efficacy of using HLH-94/2004 to treat patients with pediatric primary hemophagocytic lymphohistiocytosis.
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