A Prospective Multi-center Study for the Treatment of Chinese Children and Adolescents With Newly Diagnosed Hodgkin Lymphoma Using a Modified COG Strategy

Who is this study for? Infant to young adult patients with Non-Nodular Lymphocyte Predominant Hodgkin's Lymphoma
Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The incidence of Hodgkin's lymphoma (HL) in Chinese children and adolescents is only 1 / 10 of that in Europe and the United States, which is a rare childhood tumor. Due to the drug shortage and extremely low incidence, it has brought great difficulties to the domestic clinical research and failed to achieve the desired effect. In this study, we apply a well-documented effective protocol on newly diagnosed children and adolescents with HL to understand whether the same treatment regimens can obtain similar event free survival rates and overall survival rates and then find out the problems existing in the current clinical care of HL in China, so as to make continuous improvement in the future and prepare for innovative clinical research.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1
Maximum Age: 18
Healthy Volunteers: f
View:

• Patient must be ages 1 to 18 years at the time of diagnosis; Newly diagnosed, histologically confirmed Hodgkin disease (No nodular lymphocyte-predominant Hodgkin lymphoma)

Locations
Other Locations
China
West China Second University Hospital, Sichuan University, Chengdu, China
RECRUITING
Chengdu
Nanjing Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
RECRUITING
Nanjing
Shanghai Children's Medical Center
RECRUITING
Shanghai
Contact Information
Primary
Yi-Jin Gao
gaoyijin@scmc.com.cn
0086-21-38626161
Backup
Ya-Li Han
hanyali@scmc.com.cn
0086-21-38626161
Time Frame
Start Date: 2018-04-01
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 200
Treatments
Experimental: Low risk group
Ann Arbor stage IA or IIA without bulky disease.
Experimental: Intermediate risk group
Ann Arbor stages IB, IAE, IIB, IIAE, IIIA, IVA with or without bulk disease, and IA or IIA with bulk disease
Experimental: High risk group
Ann Arbor stages III or IV with B symptoms
Related Therapeutic Areas
Sponsors
Leads: Children's Cancer Group, China
Collaborators: Shanghai Children's Medical Center

This content was sourced from clinicaltrials.gov

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