Diagnostic Performance and Impact of a Multiplex PCR Pneumonia Panel on the Early Adaptation of Antimicrobial Therapy in ICU Patients With Severe Pneumonia. A Prospective Multicentric Observational Study.
Status: Completed
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The objective of this study is to assess the diagnostic performance of multiplex respiratory PCR (PCR-RM) compared to standard microbiological tests and its potential impact on the early adaptation of antibiotic treatment in intensive care patients with severe pneumonia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• critically ill adult patients
• clinical, biological, and radiological signs of severe pneumonia.
• community-acquired pneumonia, hospital-acquired pneumonia, or ventilator-associated pneumonia
• invasive mechanical ventilation.
Locations
Other Locations
Morocco
Avicenna Military Hospital
Marrakesh
Time Frame
Start Date: 2023-02-03
Completion Date: 2024-02-22
Participants
Target number of participants: 210
Treatments
ICU patients with severe pneumonia
Critically ill patients with severe pneumonia under mechanical ventilation including ventilator-associated pneumonia, community-acquired or hospital-acquired pneumonia.
Related Therapeutic Areas
Sponsors
Leads: Avicenna Military Hospital