HyperaldosteronismSymptoms, Doctors, Treatments, Advances & More
Hyperaldosteronism Overview
Learn About Hyperaldosteronism
Hyperaldosteronism is a condition in which the adrenal gland releases too much of the hormone aldosterone into the blood.
Hyperaldosteronism can be primary or secondary.
Conn syndrome; Mineralocorticoid excess
Hyperaldosteronism occurs when the adrenal glands release too much aldosterone.
Primary hyperaldosteronism is due to a problem of the adrenal glands themselves. Most cases are caused by a noncancerous (benign) tumor of the adrenal gland.
Secondary hyperaldosteronism is due to a problem elsewhere in the body that causes the adrenal glands to release too much aldosterone. These problems can be with:
- Genes
- Diet
- Medical disorders such as with the heart, liver, kidneys, or high blood pressure
The condition mostly affects people 30 to 50 years old and is a common cause of high blood pressure in middle age.
Primary and secondary hyperaldosteronism have common symptoms, including:
- High blood pressure
- Low level of potassium in the blood
- Feeling tired all the time
- Headache
- Muscle weakness
- Numbness
Primary hyperaldosteronism caused by an adrenal gland tumor is often treated with surgery. It can sometimes be treated with medicines.
Removing the adrenal tumor may control the symptoms. Even after surgery, some people still have high blood pressure and need to take medicine for it. But often, the number of medicines or doses can be lowered.
Limiting salt intake and taking medicine may control the symptoms without surgery. Medicines to treat hyperaldosteronism include:
- Medicines that block the action of aldosterone
- Water pills (diuretics), which help manage fluid buildup in the body
Secondary hyperaldosteronism is treated with medicines (as described above) and limiting salt intake. Surgery is usually not used.
Hironobu Sasano practices practicing medicine in Sendai, Japan. Sasano is rated as an Elite expert by MediFind in the treatment of Hyperaldosteronism. They are also highly rated in 24 other conditions, according to our data. Their clinical expertise encompasses Adrenal Gland Adenoma, Hyperaldosteronism, Adrenal Cancer, Pancreaticoduodenectomy, and Mastectomy.
Endocrine Oncology Clinic
Richard Auchus is an Endocrinologist practicing medicine in Ann Arbor, Michigan. Dr. Auchus is rated as an Elite provider by MediFind in the treatment of Hyperaldosteronism. He is also highly rated in 20 other conditions, according to our data. His clinical expertise encompasses Congenital Adrenal Hyperplasia (CAH), Intersex, Cushing's syndrome, Hormone Replacement Therapy (HRT), and Orchiectomy. Dr. Auchus is board certified in Endocrinology, Diabetes & Metabolism. Dr. Auchus is currently accepting new patients.
Endocrinology - Froedtert Hospital
James Findling is an Endocrinologist practicing medicine in Milwaukee, Wisconsin. Dr. Findling is rated as a Distinguished provider by MediFind in the treatment of Hyperaldosteronism. He is also highly rated in 26 other conditions, according to our data. His clinical expertise encompasses Cushing's syndrome, Cushing's disease, Addison's Disease, Exogenous Cushing's syndrome, and Hormone Replacement Therapy (HRT). Dr. Findling is board certified in Endocrinology, Diabetes And Metabolism and Internal Medicine. Dr. Findling is currently accepting new patients.
The outlook for primary hyperaldosteronism is good with early diagnosis and treatment.
The outlook for secondary hyperaldosteronism depends on the cause of the condition.
Primary hyperaldosteronism can cause very high blood pressure, which can damage many organs, including the eyes, kidneys, heart, and brain.
Erection problems and enlarged breast tissue in men (gynecomastia) may occur with long-term use of medicines to block the effect of hyperaldosteronism.
Contact your provider if you develop symptoms of hyperaldosteronism.
Summary: The goal of this observational study is to see if there is a cyclical or exaggerated diurnal variation in aldosterone production in people with Primary Aldosteronism.
Background: The adrenal gland makes the hormone aldosterone. This helps regulate blood pressure. An adrenal gland tumor that makes too much aldosterone can cause high blood pressure and low potassium. The cause of these tumors is unknown, but sometimes they are inherited.
Published Date: July 13, 2025
Published By: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Guber HA, Oprea M, Russell YX. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 25.
Nieman LK. Adrenal cortex. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 208.
Weiner ID, Wingo CS. Endocrine causes of hypertension: aldosterone. In: Johnson RJ, Floege J, Tonelli M, eds. Comprehensive Clinical Nephrology. 7th ed. Philadelphia, PA: Elsevier; 2024:chap 39.
Young WF. Endocrine hypertension. In. Melmed S, Auchus RJ, Goldfine AB, Rosen CJ, Kopp PA, eds. Williams Textbook of Endocrinology. 15th ed. Philadelphia, PA: Elsevier; 2025:chap 14.


