New Directions and Perspectives in the Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general population for primary osteoporosis evaluation to enhance the assessment of CKD-MBD.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 70
Healthy Volunteers: t
View:

• HD group: Patients undergoing HD for at least 12 months, aged 20-70 years, after signing an informed consent.

• KTR group: Patients with successful KTx performed at least 12 months prior to their enrollment, aged 20-70 years old, after signing an informed consent. Subjects will be eligible for inclusion regardless of KTx immunosuppression regimen, pre-transplantation history, history of pre-transplant dialysis, or whether the kidney donation was from a living or deceased donor.

• GPO group: men and postmenopausal women diagnosed with primary osteopenia or osteoporosis, aged 50-70 years old, after signing an informed consent.

Locations
Other Locations
Romania
University of Medicine and Pharmacy Grigore T. Popa
RECRUITING
Iași
Contact Information
Primary
Nada Akad, Dr.
akadnada@gmail.com
0040742015245
Time Frame
Start Date: 2025-03-19
Estimated Completion Date: 2027-06
Participants
Target number of participants: 180
Treatments
Hemodialysis group
Patients undergoing HD for at least 12 months, aged 20-70 years, after signing an informed consent.
Kidney transplant group
Patients with successful KTx performed at least 12 months prior to their enrollment, aged 20-70 years old, after signing an informed consent. Subjects will be eligible for inclusion regardless of KTx immunosuppression regimen, pre-transplantation history, history of pre-transplant dialysis, or whether the kidney donation was from a living or deceased donor.
General population osteoporosis/osteopenia
Men and postmenopausal women diagnosed with primary osteopenia or osteoporosis, aged 50-70 years old, after signing an informed consent.
Sponsors
Leads: Grigore T. Popa University of Medicine and Pharmacy

This content was sourced from clinicaltrials.gov