Learn About Hypersplenism

What is the definition of Hypersplenism?

Hypersplenism is an overactive spleen. The spleen is an organ found in the upper left side of your abdomen. The spleen helps filter old and damaged cells from your bloodstream. If your spleen is overactive, it removes the blood cells too early and too quickly.

The spleen plays a key role in helping your body fight infections. Problems with the spleen can make you more likely to develop infections.

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What are the causes of Hypersplenism?

Common causes of hypersplenism include:

  • Cirrhosis (advanced liver disease)
  • Lymphoma
  • Malaria
  • Tuberculosis
  • Various connective tissue and inflammatory diseases
What are the symptoms of Hypersplenism?

Symptoms include:

  • Enlarged spleen
  • Low level of one or more types of blood cells
  • Feeling full too soon after eating
  • Stomach pain on the left side
Spleen
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Who are the top Hypersplenism Local Doctors?
BP
Bing Peng
Elite
Highly rated in
14
conditions

Key Laboratory Of Birth Defects And Related Diseases Of Women And Children

Chengdu, CN 

Bing Peng practices in Chengdu, China. Peng is rated as an Elite expert by MediFind in the treatment of Hypersplenism. He is also highly rated in 14 other conditions, according to our data. His top areas of expertise are Hypersplenism, Splenic Neoplasm, Cavernous Lymphangioma, Endoscopy, and Gallbladder Removal.

DB
Dou-sheng S. Bai
Elite
Highly rated in
11
conditions

Clinical Medical College Of Yangzhou University

Yangzhou, CN 

Dou-sheng Bai practices in Yangzhou, China. Bai is rated as an Elite expert by MediFind in the treatment of Hypersplenism. They are also highly rated in 11 other conditions, according to our data. Their top areas of expertise are Hypersplenism, Esophageal Varices, Portal Hypertension, Endoscopy, and Liver Transplant.

 
 
 
 
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NH
Na Huang
Elite
Highly rated in
3
conditions

National & Local Joint Engineering Research Center Of Biodiagnosis And Biotherapy

Xi'an, CN 

Na Huang practices in Xi'an, China. Huang is rated as an Elite expert by MediFind in the treatment of Hypersplenism. She is also highly rated in 3 other conditions, according to our data. Her top areas of expertise are Hypersplenism, Portal Hypertension, Splenic Neoplasm, and Cirrhosis.

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What are the latest Hypersplenism Clinical Trials?
The Effects of Endoscopy Combined With Partial Splenic Artery Embolization in the Treatment of Cirrhosis With Esophageal and Gastric Varices Complicated With Hyperplenism or Splenomegaly:A Randomized Controlled Study.
Enrollment Status: Enrolling by invitation
Publish Date: March 02, 2022
Intervention Type: Procedure
Study Phase: Not Applicable

Summary: The purpose of this study was to compare the effects of partial splenic artery embolization combined with endoscopic treatment and endoscopic treatment alone on portal hypertension in cirrhosis with hyperplenism or splenomegaly in esophageal and gastric varices.

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HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)
Enrollment Status: Recruiting
Publish Date: August 17, 2021
Intervention Type: Procedure, Drug
Study Phase: Not Applicable

Summary: The development of portal hypertension is a vital event in the natural progression of cirrhosis and is associated with severe complications including gastroesophageal varices bleeding. Cirrhotic patients with hemorrhagic shock and/or liver failure caused by variceal bleeding face a mortality of 5-20%. Hepatic venous pressure gradient (HVPG) is the recommended golden standard for portal pressure as...

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What are the Latest Advances for Hypersplenism?
Minimally invasive treatment of cirrhotic secondary hypersplenism with high-intensity focused ultrasound.
Condition: Cirrhotic Secondary Hypersplenism
Journal: Scientific reports
Treatment Used: High-Intensity Focused Ultrasound (HIFU)
Number of Patients: 11
Published: November 30, 2022
Efficacy and safety of splenic artery embolization for intractable ascites using Amplatzer vascular plug versus coil after living donor liver transplantation.
Condition: Intractable Ascites (IA)
Journal: Diagnostic and interventional radiology (Ankara, Turkey)
Treatment Used: Splenic Artery Embolization (SAE) with Coil
Number of Patients: 26
Published: October 11, 2022
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Improvement of SLC29A3 spectrum disorder-related sensorineural hearing loss after initiation of IL-6 inhibitor.
Condition: SLC29A3 Spectrum Disorder-related Sensorineural Hearing Loss
Journal: BMJ case reports
Treatment Used: IL-6 Inhibitor
Number of Patients: 1
Published: June 22, 2022
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Who are the sources who wrote this article ?

Published Date: May 02, 2021
Published By: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Arber DA. Spleen. In: Goldblum JR, Lamps LW, McKenney JK, Myers JL, eds. Rosai and Ackerman's Surgical Pathology. 11th ed. Philadelphia, PA: Elsevier; 2018:chap 38.

Connell NT, Shurin SB, Schiffman F. The spleen and its disorders. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 160.