Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
• Splenomegaly with secondary hypersplenism
• Bleeding portal hypertension
• No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT
• Informed consent to participate in the study
Locations
Other Locations
China
Clinical Medical College of Yangzhou University
RECRUITING
Yangzhou
Clinical Medical College, Yangzhou University
COMPLETED
Yangzhou
Contact Information
Primary
Guo-Qing Jiang, MD
jgqing2003@hotmail.com
+86-514-87373272
Backup
Dou-sheng Bai, MD
bdsno1@hotmail.com
86-514-87373275
Time Frame
Start Date: 2026-03-25
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 15
Treatments
Experimental: Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection
Procedure/Surgery: vagus nerve-guided group The vagus nerve-guided procedure was performed in the following order: (1) find the left crural diaphragm; (2) via the surface of the left crural diaphragm, blunt dissect the left lateral surface of the distal esophagus using Bipolar Forceps, and find posterior vagal trunk; (3) along posterior vagal trunk towards left lateral esoph-agogastric junction, find and protect gastric and celiac branches; (4) enter the lesser omental sac from the right crural diaphragm using Bipolar Forceps; (5) transect the left gastric artery and vein together using a linear vascular stapler; (6) blunt dissect the anterior surface of the distal esophagus using Bipolar Forceps, and find anterior vagal trunk; (7) along anterior vagal trunk towards right lateral esoph-agogastric junction, find and protect gastric and hepatic branches; and (8) blunt dissect the right lateral surface of the distal esophagus. The hepatogastric ligament was conserved.
Related Therapeutic Areas
Sponsors
Leads: Northern Jiangsu People's Hospital