The Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by Impedance Cardiography in Early Pregnancy
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy. Patients will be given medication based on their hemodynamics and asked to return for a repeat measurement.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:
• Patients presenting to Maternal Hypertension Center at Cabell Huntington Hospital
• English speaking
• 18-45 years old.
• Willing to provide informed consent
• Gestational age prior to 15 weeks gestation
Locations
United States
West Virginia
Maternal Hypertension Center at Cabell Huntington Hospital
RECRUITING
Huntington
Contact Information
Primary
Morgan Ruley, MS
kelley115@marshall.edu
(304) 691-1458
Backup
Jesse Cottrell, MD
cottrellje@marshall.edu
(304) 691-1400
Time Frame
Start Date: 2021-03-03
Estimated Completion Date: 2025-12
Participants
Target number of participants: 60
Treatments
Beta blockade
Beta blocker (labetalol or atenolol) will be given for a cardiac output \>8 l/min.
Nifedipine
Nifedipine will be given for a mean arterial pressure \>100.
Related Therapeutic Areas
Sponsors
Leads: Marshall University