Disparities in Neurocognitive Impairment Among Hispanics/Latinos in the US With Parkinson's Disease: The Role of Cardiovascular Risk

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

This study will investigate disparities in neurocognitive impairment (NCI) among Hispanics/Latinos/as/x (henceforth Hispanics) living in the US-Mexico borderland of California or in North Carolina with Parkinson's Disease (PD) and determine mechanisms underlying these disparities. NCI is an important aspect of the clinical course of PD, particularly among Hispanics, who have increased prevalence of dementia. Among the many potential factors driving this disparity, the investigators chose to focus on a modifiable risk factor to which Hispanics are particularly vulnerable, and that has been linked to increased NCI, namely cardiovascular (CVD) risk (e.g., diabetes, hypertension, obesity).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:

• 40 years old and older

• non-Hispanic Whites

• Hispanics

• All genders

• Ability to provide consent

• Diagnosed with Parkinson's Disease

Locations
United States
California
UC San Diego
COMPLETED
La Jolla
North Carolina
Duke University
RECRUITING
Durham
Contact Information
Primary
Lizbeth C Vera Murillo, MS
lizbeth.veramurillo@duke.edu
919-681-3957
Time Frame
Start Date: 2022-09-30
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 120
Treatments
Hispanics with Parkinson's Disease
All Hispanics with PD will complete comprehensive neuromedical and neuropsychological evaluations, a blood draw and assessments of socio-cultural factors (e.g., health literacy, access to care, acculturation, bilingualism, discrimination, socioeconomic status).
non-Hispanic Whites with Parkinson's Disease
All non-Hispanic Whites with PD will complete comprehensive neuromedical and neuropsychological evaluations, a blood draw and assessments of socio-cultural factors (e.g., health literacy, access to care, acculturation, bilingualism, discrimination, socioeconomic status).
Sponsors
Leads: Duke University

This content was sourced from clinicaltrials.gov