A Randomized Controlled Trial Comparing Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT) in Reducing Intraocular Pressure in Open-Angle Glaucoma
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss. DSLT is a newer, non-contact technique that may improve comfort and efficiency. Participants will be randomly assigned to receive either DSLT or SLT and followed for 12 months to assess eye pressure, safety, and treatment outcomes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥18 years
• Diagnosis of OAG (including exfoliative or pigmentary) or OHT
• Gonioscopically open angle (visible scleral spur 360°)
• Ability to consent and comply with follow-up
Locations
United States
South Carolina
MUSC
RECRUITING
Charleston
Time Frame
Start Date: 2026-04-27
Estimated Completion Date: 2027-10
Participants
Target number of participants: 172
Treatments
Experimental: Direct Selective Laser Trabeculoplasty
This arm is going to receive the Direct SLT treatment
Active_comparator: Traditional Selective Laser Trabeculoplasty
This arm is going to receive the Traditional SLT treatment which will act as a control for the experimental arm. Note that both lasers are Standard of Care (SOC) and FDA approved
Related Therapeutic Areas
Sponsors
Leads: Medical University of South Carolina