Assessment of Retinal Vasculature Using Optical Coherence Tomography in Health, Hypertension & Chronic Kidney Disease.

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Patients with high blood pressure (hypertension) and chronic kidney disease are at an increased risk of developing heart disease and strokes. Part of this risk is due to changes in the structure and function of the blood vessels throughout the body. It is thought that reducing high blood pressure and treating chronic kidney disease improves the structure and function of blood vessels but information on this is limited. Optical coherence tomography (OCT) is a method of looking at the blood vessels at the back of the eye. It is a simple, quick and non-invasive test that you may have previously had during a visit to the optician. The purpose of the study is to ascertain whether OCT is able to detect changes in the eye's blood vessels in patients with hypertension and chronic kidney disease compared to healthy individuals and also to see if any differences seen improve with treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

• Male or female

• Age 18-80

• Body mass index ≤35

• For those with hypertension: BP ≥140/90 or on treatment for hypertension

• For those with CKD: CKD as defined by the Kidney Diseases Quality Initiative guidelines

Locations
Other Locations
United Kingdom
University of Edinburgh
RECRUITING
Edinburgh
Contact Information
Primary
Neeraj Dhaun, MD PhD
bean.dhaun@ed.ac.uk
01312429215
Backup
David Webb
d.j.webb@ed.ac.uk
01312429215
Time Frame
Start Date: 2014-05-16
Estimated Completion Date: 2028-09
Participants
Target number of participants: 150
Treatments
Treated hypertension
Patients on treatment for hypertension
CKD-ESRD
Pre- \& post haemodialysis
Healthy individuals
Healthy volunteers
Chronic kidney disease
Pre-dialysis CKD \& those with a functional renal transplant
Hypertension
Untreated
Related Therapeutic Areas
Sponsors
Leads: University of Edinburgh

This content was sourced from clinicaltrials.gov