Learn About Hypophosphatemia
Hypophosphatemia is a low level of phosphorus (phosphate) in the blood.
Low blood phosphate; Phosphate - low; Hyperparathyroidism - low phosphate
The following may cause hypophosphatemia:
- Alcoholism
- Antacids
- Certain medicines, including insulin, acetazolamide, foscarnet, imatinib, intravenous iron, niacin, pentamidine, sorafenib, and tenofovir
- Fanconi syndrome
- Fat malabsorption in the gastrointestinal tract
- Hyperparathyroidism (overactive parathyroid gland)
- Starvation
- Too little vitamin D
Symptoms may include:
- Bone pain
- Confusion
- Muscle weakness
- Seizures
Treatment depends on the cause. Phosphate can be given by mouth or through a vein (IV).
Maria Brandi practices in Florence, Italy. Brandi is rated as an Elite expert by MediFind in the treatment of Hypophosphatemia. Their top areas of expertise are Osteoporosis, Hypophosphatemia, X-Linked Hypophosphatemia, Parathyroidectomy, and Hormone Replacement Therapy (HRT).
Leanne Ward practices in Ottawa, Canada. Ms. Ward is rated as an Elite expert by MediFind in the treatment of Hypophosphatemia. Her top areas of expertise are Rickets, X-Linked Hypophosphatemia, Hypophosphatemia, and Malnutrition.
Duke Endocrinology Clinic - Clinic 1A
Thomas Weber is an Endocrinologist in Durham, North Carolina. Dr. Weber has been practicing medicine for over 36 years and is rated as an Elite provider by MediFind in the treatment of Hypophosphatemia. His top areas of expertise are Hypophosphatemia, Rickets, X-Linked Hypophosphatemia, Malnutrition, and Parathyroidectomy.
How well you do depends on what has caused the condition.
Contact your provider if you have muscle weakness or confusion.
Summary: X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells. Low phosphate leads to soft bones (rickets). Patients experience bowed legs, short stature, bone pain and dental pain. Prior to Burosumab, conventional treatment of XLH prev...
Summary: Hypophosphatemia is a common phenomenon in the ICU, and several retrospective studies have shown that hypophosphatemia is associated with prolonged mechanical ventilation in ICU patients. However, the specific mechanism and causal relationship are not clear. Previous studies have shown that phosphate infusion improves the contraction of the diaphragm induced by exogenous electrical stimulation, bu...
Published Date: December 31, 2023
Published By: Walead Latif, MD, Nephrologist and Clinical Associate Professor, Rutgers Medical School, Newark, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Chonchol M, Smogorzewski MJ, Stubbs, JR, Yu ASL. Disorders of calcium, magnesium, and phosphate balance. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector's The Kidney. 11th ed. Philadelphia, PA: Elsevier; 2020:chap 18.
Klemm KM, Klein MJ, Zhang Y. Biochemical markers of bone metabolism. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 16.
Yu ASL. Diseases of magnesium and phosphorus. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 105.