HypophosphatemiaSymptoms, Doctors, Treatments, Advances & More
Learn About Hypophosphatemia
Hypophosphatemia is a low level of phosphorus (phosphate) in the blood.
Low blood phosphate; Phosphate - low; Hyperparathyroidism - low phosphate
The following may cause hypophosphatemia:
- Alcoholism
- Antacids
- Certain medicines, including insulin, acetazolamide, foscarnet, imatinib, intravenous iron, niacin, pentamidine, sorafenib, and tenofovir
- Fanconi syndrome
- Fat malabsorption in the gastrointestinal tract
- Hyperparathyroidism (overactive parathyroid gland)
- Starvation
- Too little vitamin D
Symptoms may include:
- Bone pain
- Confusion
- Muscle weakness
- Seizures
The treatment depends on the cause. Phosphate can be given by mouth or through a vein (IV).
Maria Brandi practices practicing medicine in Florence, Italy. Brandi is rated as an Elite expert by MediFind in the treatment of Hypophosphatemia. They are also highly rated in 50 other conditions, according to our data. Their clinical expertise encompasses Osteoporosis, Hypophosphatemia, X-Linked Hypophosphatemia, Parathyroidectomy, and Hormone Replacement Therapy (HRT).
Leanne Ward practices practicing medicine in Ottawa, Canada. Ms. Ward is rated as an Elite expert by MediFind in the treatment of Hypophosphatemia. She is also highly rated in 26 other conditions, according to our data. Her clinical expertise encompasses Rickets, X-Linked Hypophosphatemia, Hypophosphatemia, and Malnutrition.
Duke Endocrinology Clinic - Clinic 1A
Thomas Weber is an Endocrinologist practicing medicine in Durham, North Carolina. Dr. Weber is rated as an Elite provider by MediFind in the treatment of Hypophosphatemia. He is also highly rated in 24 other conditions, according to our data. His clinical expertise encompasses Hypophosphatemia, Rickets, X-Linked Hypophosphatemia, Malnutrition, and Parathyroidectomy. Dr. Weber is board certified in American Board Of Internal Med, Endocrinology, Diabetes & Meta. Dr. Weber is currently accepting new patients.
How well you do depends on what has caused the condition.
Contact your provider if you have muscle weakness or confusion.
Summary: Phosphate diabetes is defined by urinary phosphate wasting due to impaired tubular reabsorption. It can be classified based on either a genetic or acquired origin. Chronic hypophosphatemia causes rickets in children, leading to growth disorders, bone deformities, and bone pain. In adults, it results in osteomalacia, pseudofractures, as well as muscle fatigue and weakness during exertion. X-linked ...
Summary: This is an international, multicentre, prospective, non-interventional, observational Registry of patients with X-Linked hypophosphatemia (XLH). The main objective of this XLH Registry is to collect data to characterise the treatment, progression and long-term outcomes of XLH in both adult and paediatric settings.
Published Date: October 23, 2025
Published By: Walead Latif, MD, Nephrologist and Clinical Associate Professor, Rutgers Medical School, Newark, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Chonchol M, Smogorzewski MJ, Stubbs, JR, Yu ASL. Disorders of calcium, magnesium, and phosphate balance. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector's The Kidney. 11th ed. Philadelphia, PA: Elsevier; 2020:chap 18.
Klemm KM, Klein MJ, Zhang Y. Biochemical markers of bone metabolism. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 16.
Yu ASL. Diseases of magnesium and phosphorus. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 105.