Effect of Hypothermia on the Correlation Between Bispectral Index (BIS) and Patient State Index (PSI) During Cardiopulmonary Bypass
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The goal of this observational study is to evaluate whether hypothermia affects the relationship between electroencephalography-derived indices during cardiac surgery in adult patients undergoing cardiopulmonary bypass. The main questions it aims to answer are: Does the correlation between Bispectral Index (BIS) and Patient State Index (PSI) change between normothermic and hypothermic phases during cardiopulmonary bypass? How do BIS and PSI values change in response to decreasing body temperature? Participants will: Undergo standard general anesthesia for elective on-pump coronary artery bypass surgery Be monitored simultaneously with BIS and PSI devices during surgery Have data recorded at predefined temperature-based time points during cardiopulmonary bypass
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age ≥18 years
• Elective on-pump Coronary Artery Bypass Grafting (CABG) surgery
• Planned use of general anesthesia
• Written informed consent
Locations
Other Locations
Turkey
Sakarya University Training and Research Hospital, Department of Anesthesiology and Reanimation
RECRUITING
Sakarya
Contact Information
Primary
AHMET R DOĞAN, M.D
a.ridvandogan@gmail.com
+905427988070
Time Frame
Start Date:2026-05-01
Estimated Completion Date:2026-12-31
Participants
Target number of participants:60
Treatments
Elective On-Pump CABG Patients Undergoing CPB
Adult patients undergoing elective on-pump coronary artery bypass grafting with cardiopulmonary bypass will be included. All participants will receive standard general anesthesia and intraoperative management according to institutional protocols. Bispectral Index (BIS) and Patient State Index (PSI) will be monitored simultaneously throughout surgery. Data will be collected at predefined time points across normothermic, hypothermic, and rewarming phases of cardiopulmonary bypass to evaluate the relationship between these indices under varying temperature conditions.