ICF Syndrome Latest Advances

Structure of human lymphoid-specific helicase HELLS in its autoinhibitory state.

Journal: bioRxiv : the preprint server for biology

Published: February 11, 2026

Clinical immunology in chromatinopathies: a scoping review.

Journal: Frontiers in immunology

Published: December 22, 2025

CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 10, 2025

Epigenetic disruption meets immune deficiency: a case report of ICF syndrome linked to DNMT3B mutation.

Journal: Frontiers in immunology

Published: November 08, 2025

Case Report: a 28-year-old female patient presented with recurrent fevers and episodes of shock due to ZBTB24 pathogenic variant.

Journal: Frontiers in immunology

Published: September 12, 2025

Missense substitutions in the BTB domain of ZBTB24 can lead to protein instability and cause ICF2 syndrome.

Journal: Human molecular genetics

Published: June 25, 2025

Congenital diseases with defects in DNA methylation maintenance: focusing on ICF syndrome and multilocus imprinting disturbance.

Journal: Genes & genetic systems

Published: June 11, 2025

Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome identified by whole-exome sequencing (WES): a case report from a developing country.

Journal: Oxford medical case reports

Published: January 25, 2025

Fatal CAEBV-Associated Vasculitis in ICF Syndrome Type 2.

Journal: Journal of investigational allergology & clinical immunology

Published: November 26, 2024

Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2.

Journal: Frontiers in immunology

Published: October 26, 2024

The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression.

Journal: Nucleic acids research

Published: October 08, 2024

In-depth immune profiling of a patient with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2 caused by a novel mutation in ZBTB24.

Journal: Clinical and experimental immunology

Published: September 30, 2024

ICF Syndrome Latest Advances

Find the Latest Research About ICF Syndrome

Structure of human lymphoid-specific helicase HELLS in its autoinhibitory state.

Structure of human lymphoid-specific helicase HELLS in its autoinhibitory state.

Clinical immunology in chromatinopathies: a scoping review.

Clinical immunology in chromatinopathies: a scoping review.

CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1.

CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1.

Epigenetic disruption meets immune deficiency: a case report of ICF syndrome linked to DNMT3B mutation.

Epigenetic disruption meets immune deficiency: a case report of ICF syndrome linked to DNMT3B mutation.

Case Report: a 28-year-old female patient presented with recurrent fevers and episodes of shock due to ZBTB24 pathogenic variant.

Case Report: a 28-year-old female patient presented with recurrent fevers and episodes of shock due to ZBTB24 pathogenic variant.

Missense substitutions in the BTB domain of ZBTB24 can lead to protein instability and cause ICF2 syndrome.

Missense substitutions in the BTB domain of ZBTB24 can lead to protein instability and cause ICF2 syndrome.

Congenital diseases with defects in DNA methylation maintenance: focusing on ICF syndrome and multilocus imprinting disturbance.

Congenital diseases with defects in DNA methylation maintenance: focusing on ICF syndrome and multilocus imprinting disturbance.

Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome identified by whole-exome sequencing (WES): a case report from a developing country.

Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome identified by whole-exome sequencing (WES): a case report from a developing country.

Fatal CAEBV-Associated Vasculitis in ICF Syndrome Type 2.

Fatal CAEBV-Associated Vasculitis in ICF Syndrome Type 2.

Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2.

Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2.

The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression.

The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression.

In-depth immune profiling of a patient with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2 caused by a novel mutation in ZBTB24.

In-depth immune profiling of a patient with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2 caused by a novel mutation in ZBTB24.