Learn About Immune Thrombocytopenia

What is the definition of Immune Thrombocytopenia?

Immune thrombocytopenia is a disorder characterized by a blood abnormality called thrombocytopenia, which is a shortage of blood cells called platelets that are needed for normal blood clotting.

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What are the causes of Immune Thrombocytopenia?

The genetic cause of immune thrombocytopenia is unclear. This condition occurs when the body's own immune system malfunctions and attacks the body's tissues and organs (autoimmunity). Normally, the immune system produces proteins called antibodies, which attach to specific foreign particles and germs, marking them for destruction. In immune thrombocytopenia, the immune system abnormally destroys platelets and makes fewer platelets than normal. People with immune thrombocytopenia produce antibodies that attack normal platelets. The platelets are destroyed and eliminated from the body, resulting in a shortage of these cells in affected individuals. Some of these antibodies also affect the cells in the bone marrow that produce platelets (known as megakaryocytes), which leads to a decrease in platelet production, further reducing the number of platelets in the blood.

How prevalent is Immune Thrombocytopenia?

The incidence of immune thrombocytopenia is approximately 4 per 100,000 children and 3 per 100,000 adults. In adults with immune thrombocytopenia, women are affected more often than men.

Is Immune Thrombocytopenia an inherited disorder?

Immune thrombocytopenia and other autoimmune disorders can run in families, but the inheritance pattern is usually unknown. People with a first-degree relative (such as a parent or sibling) with immune thrombocytopenia likely have an increased risk of developing the disorder themselves.

Who are the top Immune Thrombocytopenia Local Doctors?
Elite
Highly rated in
9
conditions
Pediatrics
Pediatric Hematology Oncology

NewYork-Presbyterian Komansky Children's Hospital

525 E 68th St 
New York, NY 10065

James Bussel is a Pediatrics specialist and a Pediatric Hematologist Oncology doctor in New York, New York. Dr. Bussel has been practicing medicine for over 47 years and is rated as an Elite doctor by MediFind in the treatment of Immune Thrombocytopenia. He is also highly rated in 9 other conditions, according to our data. His top areas of expertise are Immune Thrombocytopenia, Blood Clots, Hemophagocytic Lymphohistiocytosis, and Leukemia. He is licensed to treat patients in New York.

Elite
Highly rated in
6
conditions

Qilu Hospital Of Shandong University

Qilu Hospital, Shandong University 
Jinan, CN 

Ming Hou is in Jinan, China. Hou is rated as an Elite expert by MediFind in the treatment of Immune Thrombocytopenia. They are also highly rated in 6 other conditions, according to our data. Their top areas of expertise are Immune Thrombocytopenia, Purpura, Idiopathic Thrombocytopenic Purpura, and Thrombocytopenia.

 
 
 
 
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Elite
Highly rated in
5
conditions

Imperial College London

London, ENG, GB 

Nichola Cooper is in London, United Kingdom. Cooper is rated as an Elite expert by MediFind in the treatment of Immune Thrombocytopenia. She is also highly rated in 5 other conditions, according to our data. Her top areas of expertise are Immune Thrombocytopenia, Purpura, Idiopathic Thrombocytopenic Purpura, and Thrombocytopenia.

What are the latest Immune Thrombocytopenia Clinical Trials?
ITALIAN ADULT IMMUNE THROMBOCYTOPENIA (ITP) REGISTRY Investigation on a Dynamic Cohort of Italian Patients With Active ITP
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Intravenous Immunoglobulin Plus Oral Prednisone or High-dose Dexamethasone, for Adults With Immune Thrombocytopenia (ITP) With Moderate and Severe Bleeding: a Randomized, Multicentre Trial
Who are the sources who wrote this article ?

Published Date:updated Last, June

Published By: National Institutes of Health

What are the Latest Advances for Immune Thrombocytopenia?
Case Report: Use of Obinutuzumab as an Alternative Monoclonal Anti-CD20 Antibody in a Patient With Refractory Immune Thrombocytopenia Complicated by Rituximab-Induced Serum Sickness and Anti-Rituximab Antibodies.
Real-world impact of primary immune thrombocytopenia and treatment with thrombopoietin receptor agonists on quality of life based on patient-reported experience: Results from a questionnaire conducted in Switzerland, Austria, and Belgium.
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Rilzabrutinib, an Oral BTK Inhibitor, in Immune Thrombocytopenia.