Immunodeficiency with Hyper IgM Type 1
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Immunodeficiency with Hyper IgM Type 1 Overview

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Learn About Immunodeficiency with Hyper IgM Type 1

What is the definition of Immunodeficiency with Hyper IgM Type 1?
Hyper IgM syndrome is a type of primary immunodeficiency syndrome. Primary immunodeficiency occurs when part of a person’s immune system is missing or does not work correctly. The bodies of people with primary immunodeficiency can’t get rid of germs or protect themselves from new germs as well as they should. Primary immunodeficiencies are inherited, meaning they are passed down from parents to children. Hyper IgM syndromes are characterized by normal or elevated serum immunoglobulin M levels with absence of immunoglobulin G, A, and E. Immunoglobulins are proteins found in the blood. Hyper IgM results in a susceptibility to bacterial infections and sometimes opportunistic infections. There are five different types of hyper IgM syndromes (types 1-5). The types are distinguished by the location of the genetic change involved.
What are the alternative names for Immunodeficiency with Hyper IgM Type 1?
  • Immunodeficiency with hyper IgM type 1
  • HIGM
  • HIGM1
  • Hyper IgM immunodeficiency, x-linked
  • Hyper IgM syndrome
  • Hyper IgM syndrome 1
  • IHIS
  • X-linked hyper IgM syndrome
  • XHIM
Who are the top Immunodeficiency with Hyper IgM Type 1 Local Doctors?
Elite in Immunodeficiency with Hyper IgM Type 1
Valentina Vavassori
Elite in Immunodeficiency with Hyper IgM Type 1
Valentina Vavassori
Milan, IT 

Valentina Vavassori practices in Milan, Italy. Ms. Vavassori is rated as an Elite expert by MediFind in the treatment of Immunodeficiency with Hyper IgM Type 1. Her top areas of expertise are Immunodeficiency with Hyper IgM Type 1 and X-Linked Severe Combined Immunodeficiency.

Elite in Immunodeficiency with Hyper IgM Type 1
Dr. Caroline Kuo
Pediatrics
Elite in Immunodeficiency with Hyper IgM Type 1
Dr. Caroline Kuo
Pediatrics

Office

200 Medical Plz Ste 265, 
Los Angeles, CA 
310-825-0867
Languages Spoken:
English
See accepted insurances

Caroline Kuo is a Pediatrics provider in Los Angeles, California. Dr. Kuo is rated as an Elite provider by MediFind in the treatment of Immunodeficiency with Hyper IgM Type 1. Her top areas of expertise are Immunodeficiency with Hyper IgM Type 1, Severe Combined Immunodeficiency (SCID), X-Linked Agammaglobulinemia, and X-Linked Severe Combined Immunodeficiency.

 
 
 
 
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Elizabeth K. Knight
Experienced in Immunodeficiency with Hyper IgM Type 1
Dr. Elizabeth K. Knight
Hematology | Oncology
Experienced in Immunodeficiency with Hyper IgM Type 1
Dr. Elizabeth K. Knight
Hematology | Oncology

Advocate Infusion Center

1800 Hollister Dr, Ste 112, 
Libertyville, IL 
847-367-6781
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Elizabeth Knight is a Hematologist and an Oncologist in Libertyville, Illinois. Dr. Knight is rated as an Experienced provider by MediFind in the treatment of Immunodeficiency with Hyper IgM Type 1. Her top areas of expertise are Inflammatory Breast Cancer, Angiosarcoma, Paget Disease of the Breast, Familial Colorectal Cancer, and Bone Marrow Aspiration.

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What are the latest Immunodeficiency with Hyper IgM Type 1 Clinical Trials?
Prospective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Prospective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Enrollment Status: Recruiting
Publish Date: September 04, 2025

Background: Pyrimidine and purine metabolism disorders (DPPMs) affect how the body metabolizes chemicals called pyrimidines and purines. DPPMs can cause dysfunctions throughout the body, especially in the brain, blood, kidneys, and immune system. People with DPPMs might have no symptoms, mild symptoms, or they may have severe, chronic symptoms, that can be fatal. DPPMs are not well understood, and researchers...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center