Intrauterine Platelet Rich Plasma (PRP) Infusion for Endometrial Insufficiency: A Prospective, Double-Blind, Placebo-Controlled Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To determine the effectiveness of an intrauterine PRP infusion on endometrial thickness and in vitro fertilization (IVF) outcomes in a population of infertile women with a history of unresponsive thin endometrium.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:
• Patients who have previously undergone at least 2 unsuccessful frozen embryo transfer cycles, defined as failure to achieve a sustained clinical pregnancy (visualization of intrauterine gestational sac on ultrasound or a cancelled embryo transfer cycle due to inadequate endometrial thickness
• Patients with a diagnosis of thin endometrial lining (less than or equal to 6 mm maximum thickness) during prior unsuccessful or canceled embryo transfer cycles.
Locations
United States
New Jersey
Reproductive Medicine Associates of New Jersey
RECRUITING
Basking Ridge
Contact Information
Primary
Christine V Whitehead, BSN, RN
clinicalresearchteam@ivirma.com
19736562841
Backup
Caroline Zuckerman, BS
clinicalresearchteam@ivirma.com
19736562841
Time Frame
Start Date: 2022-10-15
Estimated Completion Date: 2025-12
Participants
Target number of participants: 62
Treatments
Active_comparator: Intervention Group
an intrauterine infusion of platelet rich plasma (PRP) will be administered to this group
Placebo_comparator: Control Group
an intrauterine infusion of normal saline will be administered to this group
Related Therapeutic Areas
Sponsors
Leads: Reproductive Medicine Associates of New Jersey