A Single-center Randomized Controlled Trial on Mevalproic Acid Improving Oocyte Quality and Embryo Development in Elderly Infertile Patients
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this clinical trial is to test MVA on improving pregnancy outcome in elderly infertile patients undergoing invitro fertilization (IVF). The main question it aims to answer is whether MVA could improve embryo haploid rate. Participants requested IVF are asked to randomly culture equal numbers of oocyte and embryo with or without MVA. Therefore, sibling oocytes were randomly divided into test group and control group.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 38
Maximum Age: 42
Healthy Volunteers: f
View:
• 38 years ≤ age ≤ 42 years;
• Number of IVF/ICSI cycles ≤ 2
Locations
Other Locations
China
Reproductive Medicine Center, The affiliated Drum Towel Hospital of Nanjing University Medical School
RECRUITING
Nanjing
Contact Information
Primary
Haixiang Sun, MD
haixiang_sun@nju.edu.cn
025-83106666
Backup
Jie Mei, MD
meijie560@163.com
Time Frame
Start Date: 2022-10-08
Estimated Completion Date: 2025-12
Participants
Target number of participants: 148
Treatments
Experimental: MVA treated group
Oocytes in this groups will be cultured with MVA
No_intervention: Control group
Oocytes in this groups will be culture without MVA
Related Therapeutic Areas
Sponsors
Leads: Nanjing University