Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well. This study will determine if a medicine given by mouth will improve sperm motility in men with spinal cord injuries. The medicine is called probenecid.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:
• Subject has a traumatic spinal cord injury.
• Subject is male and is 18 years or older.
Locations
United States
Florida
University of Miami
RECRUITING
Miami
Contact Information
Primary
Odaro Ugbo, BSc
oxu32@miami.edu
305-243-1491
Backup
Orrey Padilla
oxp210@med.miami.edu
305-243-1491
Time Frame
Start Date: 2024-01-18
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 90
Treatments
Experimental: Full dose group
Participants in this group will receive the full dose of probenecid for a total of 90 days.
Experimental: Half dose group
Participants in this group will receive half the dose of probenecid for a total of 90 days.
Placebo_comparator: Control-placebo group
Participants in this group will receive a placebo dose (No active ingredient) for a total of 90 days.
Related Therapeutic Areas
Sponsors
Collaborators: United States Department of Defense
Leads: University of Miami