Double vs Single Intrauterine Insemination in Male Factor Infertility - a Multicenter Randomized Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of the study is to compare the pregnancy outcomes of single vs double intrauterine insemination (IUI) in couples with male factor infertility.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: t
View:
• Couples trying to conceive for at least 6 months despite of regular sexual intercourse
• Female partner between 18-40 years old
• Male partner sperm analysis total motile sperm count between 1-10 million in at least 2 sperm analysis on different days.
Locations
Other Locations
Turkey
Umraniye Training and Research Hospital
RECRUITING
Istanbul
Contact Information
Primary
Merve Dizdar, Speacialist
mervedizdar@gmail.com
+905355962232
Backup
Gürkan Bozdağ, Professor
gbozdag75@yahoo.com
+905327136326
Time Frame
Start Date: 2023-06-05
Estimated Completion Date: 2024-12-22
Participants
Target number of participants: 264
Treatments
Placebo_comparator: Single intrauterine insemination group
When the leading follicle is greater than 17 mm following ovulation induction with follicle stimulating hormone (FSH) daily injections, ovulation trigger injection will be given to the participant. 36 hours after ovulation trigger injection single intrauterine insemination with partner's sperm collected on the same day will be done.
Experimental: Double intrauterine insemination group
When the leading follicle is greater than 17 mm following ovulation induction with follicle stimulating hormone (FSH) daily injections, ovulation trigger injection will be given to the participant. 24 and 48 hours after ovulation trigger injection intrauterine insemination will be done twice with partner's sperm collected on the specified days.
Related Therapeutic Areas
Sponsors
Leads: Umraniye Education and Research Hospital