Impact of Endometrial Compaction on Reproductive Outcomes After Cryotransfer of Euploid Embryos in a Natural Cycle: Prospective Cohort Study
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
Multicenter prospective observational cohort study, comparing ongoing pregnancy rates in natural cycles for euploid embryo transfer in patients who present endometrial compaction at the time of the transfer versus those who have a stable or greater endometrial thickness with respect to the estrogenic phase.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:
• Aged 18 to 50 years
• Primary or secondary infertility
• Normal uterine cavity
• Endometrial preparation in a modified natural cycle for single embryo transfer
• Embryo in blastocyst state from own oocyte or oocyte donation cycles, who had normal results on preimplantation genetic testing for aneuploidy (PGT-A) via trophectoderm biopsy.
Locations
Other Locations
Spain
Instituto Bernabeu
RECRUITING
Madrid
Contact Information
Primary
Esperanza E de la Torre Pérez, Gynecologist
espe_delatorre@hotmail.com
+34625072082
Backup
Juan Carlos J Castillo Farfan, Doctor
jcastillo@institutobernabeu.com
+34650562634
Time Frame
Start Date: 2022-06-15
Estimated Completion Date: 2025-06-15
Participants
Target number of participants: 206
Treatments
exposed or compaction group
103 women with a decrease of ≥ 5% in endometrial thickness between the estrogenic phase (ovulation induction day) and the day of embryo transfer (7 days after ovulation induction).
non-exposed non-compaction group
103 women with similar or greater endometrial thickness between the estrogenic phase (ovulation induction day) and the day of embryo transfer (7 days after ovulation induction).
Related Therapeutic Areas
Sponsors
Leads: Instituto Bernabeu
Collaborators: Universidad Miguel Hernandez de Elche