Immediate Versus Postponed Single Blastocyst Transfer in Programmed or Stimulated Cycle Frozen Embryo Transfer: a Multicenter Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this randomized controlled trial is to examine whether single blastocyst transfer in the first cycle after oocyte retrieval (immediate) is non-inferior to single blastocyst transfer in a subsequent cycle (postponed) in stimulated or programmed cycle frozen embryo transfer (FET). The primary outcome is live birth rate.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:
• Eligible for FET in a programmed- or stimulated cycle immediately following a fresh embryo transfer or freeze all cycle
• Oligo-anovulatory women (cycle length \> 35 days)
• Ovulatory women (cycle length 21-35 days)
• At least one vitrified day 5 or 6 blastocyst with Gardner score of ≥ 3BB at the day of vitrification
Locations
Other Locations
Denmark
Fertility Departmen, Rigshospitalet
RECRUITING
Copenhagen
Contact Information
Primary
Anja B Pinborg, Prof., DMSC
anja.bisgaard.pinborg@regionh.dk
0045 35 45 64 30
Time Frame
Start Date: 2024-02-01
Estimated Completion Date: 2028-08-01
Participants
Target number of participants: 484
Treatments
Experimental: Immediate FET in a stimulated or programmed cycle
Stimulated or programmed cycle FET is performed in the first cycle following failed fresh embryo transfer or freeze all.
No_intervention: Postponed FET in a stimulated or programmed cycle
Stimulated or programmed cycle FET is performed at least one full menstrual, or one hormonal replacement treatment (HRT) cycle in case of oligo-anovulation, after the fresh embryo transfer or freeze-all cycle
Related Therapeutic Areas
Sponsors
Leads: Rigshospitalet, Denmark