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Aromatherapy for Mental Health Promotion in In Vitro Fertilization Patients: a Randomized Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Combination product
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The experience of infertility can cause significant emotional instability, especially for patients awaiting In Vitro Fertilization (IVF) treatment, generating anxiety, stress, and depressive symptoms. This study is a randomized clinical trial assessing the effectiveness of aromatherapy in improving mental health and quality of life in women undergoing infertility treatment. 120 participants will be randomized into three groups (Intervention, Placebo, and Control). The intervention involves the inhalation of true lavender essential oil (Lavandula angustifolia) for four weeks.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Female gender, age over 18 years.

• Diagnosis of infertility with indication for In Vitro Fertilization (IVF).

• Patients on the waiting list at HC-UFMG.

• Agreement not to practice other mind-body or herbal complementary therapies during the study.

• DASS-21 screening score compatible with at least mild anxiety, stress, and/or depression.

• No aversion to inhaling essential oil or synthetic lavender essence.

Locations
Other Locations
Brazil
Department of Obstetrics and Gynecology - Federal University of Minas Gerais - Brazil
RECRUITING
Belo Horizonte
Contact Information
Primary
Rubens L C Tavares, MD, PhD
rubens.ufmg@gmail.com
+55 31 3409-9764
Backup
Bárbara P Aquino, MSc
babiaquino.aromaterapia@gmail.com
Time Frame
Start Date: 2026-03
Estimated Completion Date: 2026-12
Participants
Target number of participants: 120
Treatments
Experimental: Lavender essential oil group
This intervention group will inhale 5 drops of true lavender essential oil (Lavandula angustifolia), administered via personal inhalers (olfactory sticks). The use of personal inhalers is a safe and widely used low-cost intervention that can be applied practically and accessibly, ensuring greater adherence to the protocol by the participants. The inhalation will be performed daily, upon waking in the morning and at night before sleeping, for four weeks.
Placebo_comparator: Synthetic lavender aroma group
The placebo group will inhale 5 drops of a synthetic lavender aroma, also administered via personal inhalers. Inhalation will be performed daily, upon waking in the morning and at night before sleeping, for four weeks.
No_intervention: Control Group
The control group will receive routine care throughout the 4 weeks.
Related Therapeutic Areas
Sponsors
Leads: Federal University of Minas Gerais

This content was sourced from clinicaltrials.gov