Gamete Treatment to Correct Fertilization Failure
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
In this proposed research study, the investigators plan to assess the efficacy of gametes' (egg and sperm) treatment on fertilization as well as pre- and post-implantation embryo development.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 89
Healthy Volunteers: f
View:
• Patients with complete fertilization failure with standard IVF or failure with one prior ICSI treatment cycle
Locations
United States
New York
Center fo Reproductive Medicine
RECRUITING
New York
Contact Information
Primary
Rodriq Stubbs, NP
res2011@med.cornell.edu
646-962-3276
Backup
Iman Mohammed, MPH
ibm4001@med.cornell.edu
646-962-3274
Time Frame
Start Date: 2007-09
Estimated Completion Date: 2027-11-30
Participants
Target number of participants: 1200
Treatments
Experimental: gamete treatment- oocytes and sperm
The spermatozoa will be prepared in the standard fashion and utilized for injection after exposure to a membrane permeabilizing agent. Patient specimen will be selected through a synthetic, sterile, single-use, culture-tested mesh. The specimen will then be placed in a 37°C environment. After 30 minutes, the selected portion is retrieved from the other side of the mesh. The injected oocytes will be then exposed to the previously mentioned activating agents for the purpose of inducing embryo development. The successfully fertilized oocytes will be further kept in culture for up to 5 days as per standard IVF/ICSI.
Authors
Related Therapeutic Areas
Sponsors
Leads: Weill Medical College of Cornell University