Learn About Inflammatory Myofibroblastic Tumor

What is the definition of Inflammatory Myofibroblastic Tumor?
An Inflammatory myofibroblastic tumor (IMT) is an uncommon, usually benign (non-cancerous) tumor made up of cells called myofibroblastic spindle cells. It usually develops in children or young adults, but can affect people of any age. An IMT can occur in almost any part of the body but is most commonly found in the lung, orbit (eye socket), peritoneum (lining of the abdominal cavity and internal organs), and mesentery. Signs and symptoms vary depending on the site of the tumor. Some people with an IMT are asymptomatic, while others may have nonspecific respiratory symptoms, fever, or pain. IMTs may recur, and become locally invasive and/or spread (metastasize) to other parts of the body. However, malignant (cancerous) IMTs are rare. The underlying cause of IMTs is poorly understood. Some cases have been linked to translocations involving the ALK gene.
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What are the alternative names for Inflammatory Myofibroblastic Tumor?
  • Inflammatory myofibroblastic tumor
  • Inflammatory fibrosarcoma
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What are the latest Inflammatory Myofibroblastic Tumor Clinical Trials?
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Blood and Lymph Node Malignancy

Background: Individuals may be prone to develop blood or lymph node cancers (leukemia or lymphoma) for a variety of reasons, including genetic predisposition to these cancers, environmental exposures or other medical conditions. Studies of people and families at high risk of cancer often lead to clues about their cause that may also be important regarding the sporadic occurrence of these cancers in the genera...

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Lymphoid Malignancies and Precursors: Tissue Acquisition Protocol

Background: - Lab studies help researchers better understand cancer biology. This information may lead to new methods for diagnosing or treating cancer. To develop these studies, researchers want to collect samples from people with cancer or precancer conditions of the lymph system. These conditions include multiple myeloma, different types of lymphoma, and adult leukemia/lymphoma. The samples collected will ...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Inflammatory Myofibroblastic Tumor?
Transanal total mesorectal excision for treating a lower rectal inflammatory myofibroblastic tumor: A case report.
Inflammatory Myofibroblastic Tumor of the Orbit in a 5-Month-Old Infant.
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Endoscopic therapy combined with photodynamic therapy for intratracheal inflammatory myofibroblastic tumor.