Evaluation of Next-Generation Sequencing-based Metabarcoding Versus Culturing in Infectious Keratitis
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
Infectious keratitis is a potential sight threatening condition. In conventional clinical practice culturing is performed in order to identify the causative microbial organism; however in recent years Next Generation Sequencing for the presence of ribosomal DNA from bacteria, fungi, or amoeba has become available. The present study aims to compare conventional culturing with Next Generation Sequencing for identifying microorganism causing keratitis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• \- Patients with a corneal infiltrate of minimum 2 mm in diameter or of 1 mm diameter within the central 6 mm of the cornea
Locations
Other Locations
Denmark
Department of Ophthalmology, Aarhus University Hospital
RECRUITING
Aarhus
Time Frame
Start Date: 2021-12-09
Estimated Completion Date: 2024-06-01
Participants
Target number of participants: 100
Related Therapeutic Areas
Sponsors
Leads: Aarhus University Hospital