Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy for Herniated Lumbar Discs Is There a Role? - A Randomized Control Trial
Who is this study for? Patients with Lumbar Disc Herniation
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Presenting to the University of Missouri hospital system - including the University of Missouri Hospital and Missouri Orthopaedic Institute - with a clinical assessment indicative of a lumbar disc herniation
• Failed conservative treatment - rest, anti-inflammatory medications, physical therapy
• Radiculopathy present - positive tension signs or sensory/motor neurologic deficits present
• Recent MRI confirming single-level lumbar disc herniation corresponding to clinical evaluation
Locations
United States
Missouri
Missouri Orthopaedic Institute
RECRUITING
Columbia
Contact Information
Primary
Vickci Jones, MEd, CCRP
jonesvicki@health.missouri.edi
(573) 882-7583
Time Frame
Start Date: 2019-11-21
Estimated Completion Date: 2026-10
Participants
Target number of participants: 200
Treatments
Placebo_comparator: Placebo Group
Patients in this group will be given the placebo (sterile saline).
Active_comparator: Dexamethasone Group
Patients in this group will be given the study drug (dexamethasone).
Authors
Related Therapeutic Areas
Sponsors
Leads: University of Missouri-Columbia