Treatment of Anaemia After Caesarean With Intravenous Versus Oral Iron and Postpartum Depression: a Multicentric Randomized Open-labelled Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The objectif of the IRON-DEP Study is to assess the efficacy of intravenous (IV) versus oral iron treatment on the prevalence of postpartum depression (PPD) in women with moderate iron deficiency anemia after caesarean delivery.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Ferritinemia ≤ 100 ng/mL OR transferrin saturation ≤ 20% measured after postoperative Hb level measurement
• EPDS score in the immediate postpartum \<11 with a never answer to question n°10
Locations
Other Locations
France
CHU Armand -Trousseau, AP-HP Service d'anesthésie-réanimation chirurgicale
RECRUITING
Paris
Contact Information
Primary
Marie-Pierre BONNET, MD, PhD
marie-pierre.bonnet@aphp.fr
(+) 33 1 71 73 89 56
Backup
Sarra POCHON, MD
sarra.pochon@aphp.fr
0033 1 42 16 75 74
Time Frame
Start Date: 2025-10-22
Estimated Completion Date: 2028-10-30
Participants
Target number of participants: 2860
Treatments
Experimental: Intravenous iron
Women in the experimental arm will receive an IV iron infusion within 5 days after delivery
Active_comparator: Oral iron
Women in the comparator arm will receive oral iron supplementation for 8 weeks after delivery
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris