Irregular Sleep-Wake SyndromeSymptoms, Doctors, Treatments, Advances & More
Irregular Sleep-Wake Syndrome Overview
Learn About Irregular Sleep-Wake Syndrome
Irregular sleep-wake syndrome is sleeping without any real schedule.
Sleep-wake syndrome - irregular; Circadian rhythm sleep disorder - irregular sleep-wake type
This disorder is very rare. It usually occurs in people with a brain function problem who also don't have a regular routine during the day. The total sleep time is normal, but the body clock loses its normal circadian cycle.
People with changing work shifts and travelers who often change time zones may also have these symptoms. These people have a different condition, such as shift work sleep disorder or jet lag syndrome.
Symptoms may include any of the following:
- Sleeping or napping more than usual during the day
- Trouble falling asleep and staying asleep at night
- Waking up often during the night
The goal of treatment is to help the person return to a normal sleep-wake cycle. This may involve:
- Setting up a regular daytime schedule of activities and mealtimes.
- Not staying in bed during the day.
- Using bright light therapy in the morning and taking melatonin at bedtime. (In older people, especially those with dementia, sedatives such as melatonin are not advised.)
- Making sure the room is dark and quiet at night.
Franciscan Medical Clinic On Pt. Fosdick
Alma Glamzi is a primary care provider, practicing in Family Medicine in Gig Harbor, Washington. Dr. Glamzi is rated as an Experienced provider by MediFind in the treatment of Irregular Sleep-Wake Syndrome. She is also highly rated in 13 other conditions, according to our data. Her clinical expertise encompasses Obesity, Obesity in Children, High Cholesterol, and Type 2 Diabetes (T2D). Dr. Glamzi is board certified in American Board Of Family Medicine. Dr. Glamzi is currently accepting new patients.
Franciscan Medical Clinic - Burien
Maria Flores is a primary care provider, practicing in Family Medicine in Burien, Washington. Dr. Flores is rated as an Experienced provider by MediFind in the treatment of Irregular Sleep-Wake Syndrome. She is also highly rated in 3 other conditions, according to our data. Her clinical expertise encompasses Type 2 Diabetes (T2D), Osteomyelitis in Children, Obesity, and Obesity in Children. Dr. Flores is board certified in American Board Of Family Medicine. Dr. Flores is currently accepting new patients.
Texas Health Family Care
Cynthia Shughrue is a primary care provider, practicing in Family Medicine in Dallas, Texas. Dr. Shughrue is rated as an Experienced provider by MediFind in the treatment of Irregular Sleep-Wake Syndrome. She is also highly rated in 6 other conditions, according to our data. Her clinical expertise encompasses Familial Combined Hyperlipidemia, Xanthoma, Cirrhosis, and High Cholesterol. Dr. Shughrue is currently accepting new patients.
The outcome is often good with treatment. But some people continue to have this disorder, even with treatment.
Most people have sleep disturbances on occasion. If this type of irregular sleep-wake pattern occurs regularly and without cause, see your provider.
Published Date: May 04, 2026
Published By: Andrew Schriber, MD, FCCP, Specialist in Pulmonary, Critical Care, and Sleep Medicine, Virtua Memorial Hospital, Mount Holly, New Jersey. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Abbott S, Reid KJ, Zee PC. Circadian disorders of the sleep-wake cycle. In: Kryger M, Roth T, Goldstein CA, Dement WC, eds. Principles and Practice of Sleep Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 43.
Auger RR, Burgess HJ, Emens JS, Deriy LV, Thomas SM, Sharkey KM. Clinical practice guideline for the treatment of intrinsic circadian rhythm sleep-wake disorders: advanced sleep-wake phase disorder (ASWPD), delayed sleep-wake phase disorder (DSWPD), non-24-hour sleep-wake rhythm disorder (N24SWD), and irregular sleep-wake rhythm disorder (ISWRD). An update for 2015: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2015:11(10):1199-1236. PMID: 26414986 pubmed.ncbi.nlm.nih.gov/26414986/.
Avidan AY. Sleep and its disorders. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 101.
Oyegbile T, Videnovic A. Irregular sleep-wake rhythm disorder. Neurol Clin. 2019;37(3):553-561. PMID: 31256789 pubmed.ncbi.nlm.nih.gov/31256789/.
Vaughn BV, Basner RC. Sleep disorders. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 374.


