Latest Advances

  • Condition: Multiple Endocrinopathies, Hypercalcemia and Pancreatitis Following Combined Immune Checkpoint Inhibitor (ICI) Use
  • Journal: BMC endocrine disorders
  • Treatment Used: Zoledronic Acid and Oral Prednisolone
  • Number of Patients: 1
  • Published —
This case report describes a 46-year old Caucasian female with malignant melanoma and lung metastases who developed multiple endocrinopathies, hypercalcemia, and pancreatitis following combined immune checkpoint inhibitor use treated with zoledronic acid and oral prednisolone.
  • Condition: Congenital Adrenal Hyperplasia (CAH) and 17a-Hydroxylase Deficiency
  • Journal: BMC endocrine disorders
  • Treatment Used: Flash Glucose Monitoring System (FGMS) Applied to Cortisol Treatment
  • Number of Patients: 1
  • Published —
This article reviewed the effectiveness of flash glucose monitoring system (method of glucose testing; FGMS) applied to cortisol (steroid hormone) treatment in a patient with congenital adrenal hyperplasia (group of genetic disorders that affect the adrenal glands; CAH) and 17?-hydroxylase deficiency (rare form of congenital adrenal hyperplasia).
  • Condition: Hypopituitarism in PROP1 Mutation Siblings
  • Journal: Pituitary
  • Treatment Used: Growth Hormone Replacement
  • Number of Patients: 5
  • Published —
This case report discusses adult siblings with combined hypopituitarism (CPHD) caused by PROP1 mutations never treated for hormone deficiencies subsequently treated with hormone replacement, hydrocortisone, and sex hormones.
  • Condition: Autoimmune Polyendocrine Syndrome Type 1 (APS-1)
  • Journal: Medicine
  • Treatment Used: Glucocorticoid, Corticosteroid, and Levothyroxine Replacement Therapy
  • Number of Patients: 1
  • Published —
This case report describes a patient with APS-1 that was treated using replacement therapy.
  • Condition: Familial Mediterranean Fever
  • Journal: The American journal of case reports
  • Treatment Used: Physiological Glucocorticoids
  • Number of Patients: 0
  • Published —
This case report describes a Japanese patient with familial Mediterranean fever and adrenocorticotropic hormone deficiency who was non-compliant with hydrocortisone replacement therapy.
  • Condition: Autoimmune Polyglandular Syndrome Type 2 (APS2)
  • Journal: Revista da Associacao Medica Brasileira (1992)
  • Treatment Used: Insulin Therapy, Prednisolone, and Fludrocortisone
  • Number of Patients: 1
  • Published —
This case report describes a 42-year-old woman with a history of total thyroidectomy due to Graves' disease, type 2 diabetes mellitus, and hypertension, who was diagnosed with autoimmune polyglandular syndrome type 2 (APS 2) treated with insulin therapy, prednisolone, and fludrocortisone.
  • Condition: Fertility Issues in Aggressive Pituitary Tumors
  • Journal: Reviews in endocrine & metabolic disorders
  • Treatment Used: Various Treatments
  • Number of Patients: 0
  • Published —
This article discusses the treatment of fertility issues in aggressive pituitary tumors.
  • Condition: Gastric Cancer Metastasis of the Peritoneum
  • Journal: Gan to kagaku ryoho. Cancer & chemotherapy
  • Treatment Used: Nivolumab
  • Number of Patients: 1
  • Published —
This study evaluated the incidence of isolated adrenocorticotropic hormone (ACTH) deficiency in a patient with gastric cancer metastasis of the peritoneum (cancer has spread to the peritoneum) was treated with nivolumab.
  • Condition: Insulinoma Associated with Adrenocorticotropic Insufficiency and Hypergonadotropic Hypogonadism
  • Journal: The Pan African medical journal
  • Treatment Used: Hydrocortisone
  • Number of Patients: 0
  • Published —
This case report describes a a 68-year old patient diagnosed with insulinoma associated with adrenocorticotropic insufficiency and hypergonadotropic hypogonadism treated with hydrocortisone.
  • Condition: Patient with Mismatch-Repair Deficiency Pituitary ACTH-Secreting Adenoma
  • Journal: Anti-cancer drugs
  • Treatment Used: Checkpoint Inhibitor Pembrolizumab
  • Number of Patients: 1
  • Published —
This case report discusses rapid disease progression to pembrolizumab in a patient with a MMRd pituitary adrenocorticotropic hormone (ACTH)-secreting adenoma.
  • Condition: Progression of Hypopituitarism and Hypothyroidism after Treatment with Pembrolizumab in a Patient with Adrenal Metastasis from Non-Small-Cell Lung Cancer
  • Journal: Internal medicine (Tokyo, Japan)
  • Treatment Used: Discontinuation of Pembrolizumab
  • Number of Patients: 1
  • Published —
This case report discusses the progression of hypopituitarism and hypothyroidism after treatment with pembrolizumab in a patient with adrenal metastasis of non-small-cell lung cancer.
  • Condition: Pituitary-Adrenal Dysfunction Caused by Nivolumab for Head and Neck Cancer
  • Journal: Auris, nasus, larynx
  • Treatment Used: Hydrocortisone Replacement Therapy
  • Number of Patients: 1
  • Published —
This case report presents a pituitary-adrenal dysfunction to isolated adrenocorticotropic hormone (ACTH) deficiency as an immune-related adverse events (irAE) of nivolumab in a patient treated for head and neck cancer.
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