Condition 101 About Juvenile Dermatomyositis

What is the definition of Juvenile Dermatomyositis?

Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis. It typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures. Children with juvenile dermatomyositis may have difficulty swallowing and breathing, and the heart may also be affected.  About 20 to 30 percent of children with juvenile dermatomyositis develop calcium deposits in the soft tissue. Affected children may not show higher than normal levels of the muscle enzyme creatine kinase in their blood but have higher than normal levels of other muscle enzymes. Treatment is aimed at addressing the individual symptoms of each patient. This may involve a combination of medications, physical therapy and supplements.

What are the alternative names for Juvenile Dermatomyositis?

  • Juvenile DM

Latest Advances On Juvenile Dermatomyositis

  • Condition: Antimelanoma Differentiation-associated Gene 5 Dermatomyositis with Interstitial Lung Disease and Cutaneous Ulcers
  • Journal: BMJ case reports
  • Treatment Used: Corticosteroids, Mycophenolate Mofetil, and Intravenous Immunoglobulin
  • Number of Patients: 1
  • Published —
The study researched the outcomes of treatment of a patient with antimelanoma differentiation-associated gene 5 complicated by interstitial lung disease and cutaneous ulcers.
  • Condition: Antimelanoma Differentiation-associated Gene 5 Antibody-positive Clinically Amyopathic Dermatomyositis
  • Journal: Medicine
  • Treatment Used: Tofacitinib
  • Number of Patients: 1
  • Published —
In this study, researchers evaluated the outcomes of using tofacitinib for the treatment of recurrence of antimelanoma differentiation-associated gene 5 antibody-positive clinically amyopathic dermatomyositis.

Clinical Trials For Juvenile Dermatomyositis

Clinical Trial
  • Status: Not yet recruiting
  • Participants: 50
  • Start Date: November 1, 2020
Laryngeal Manifestations of Connective Tissue Diseases
Clinical Trial
  • Status: Recruiting
  • Participants: 5000
  • Start Date: August 4, 2020
Rheumatology Patient Registry and Biorepository