Assessment of Macrophage Activation syndromE in STill's Disease: Retrospective Chart Analysis of Patient hIstory, Symptom Resolution and TreAtment Characteristics in Italy (AMETISTA)

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

Assessment of macrophage activation syndrome in Still's disease: retrospective chart analysis of patient history, symptom resolution and treatment characteristics in Italy

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Maximum Age: 80
Healthy Volunteers: f
View:

• Age \>6 months and ≤80 years at the beginning of the index MAS episode.

• Diagnosis of Still's disease (sJIA or AOSD diagnosis).

• Diagnosis of MAS according to treating physician in the medical record.

• Patients who have received at least 3 consecutive days of GC after diagnosis of MAS and/or are judged by the Investigator to be refractory to GC due to clinical worsening of patient's condition.

• The onset of the index MAS episode occurred between 01 January 2012 and 30 September 2022.

• According to local regulations, waivers of consent will be sought for study participants from the appropriate regulatory authorities and/or the independent ethics committee (IEC)/institutional review board (IRB). o For patients not covered by waivers of consent, signed, and dated informed consent provided by the patient, or the patient's legally authorized representative(s) for patients under the legal age (with patient assent, as applicable) or who have died, should be obtained before any study-related activities are undertaken.

Locations
Other Locations
Italy
Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico
RECRUITING
Milan
Ospedale Pediatrico Bambin Gesù
RECRUITING
Rome
Contact Information
Primary
Study Physician
medical.info@sobi.com
+4686972000
Time Frame
Start Date: 2025-06-06
Estimated Completion Date: 2025-09
Participants
Target number of participants: 35
Sponsors
Leads: Swedish Orphan Biovitrum

This content was sourced from clinicaltrials.gov