Juvenile Primary OsteoporosisSymptoms, Doctors, Treatments, Advances & More
Learn About Juvenile Primary Osteoporosis
Juvenile primary osteoporosis is a skeletal disorder characterized by thinning of the bones (osteoporosis) that begins in childhood. Osteoporosis is caused by a shortage of calcium and other minerals in bones (decreased bone mineral density), which makes the bones brittle and prone to fracture. Affected individuals often have multiple fractures in the long bones of the arms and legs, especially in the regions where new bone forms (metaphyses). They also have fractures in the bones that form the spine (vertebrae), which can cause collapse of the affected vertebrae (compressed vertebrae). Multiple fractures can cause bone pain and lead to movement problems.
Mutations in the LRP5 gene can cause juvenile primary osteoporosis. This gene provides instructions for making a protein that participates in a chemical signaling pathway that affects the way cells and tissues develop. In particular, the LRP5 protein is involved in the regulation of bone mineral density.
The prevalence of juvenile primary osteoporosis is unknown. Nearly 1 in 10 adults over age 50 have osteoporosis, but the condition is uncommon in children. Osteoporosis can occur at a young age as a feature of other conditions but rarely occurs without other signs and symptoms (primary osteoporosis).
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
Bassett Health Center Cobleskill
. Dr. Strasser is rated as a Distinguished provider by MediFind in the treatment of Juvenile Primary Osteoporosis. His top areas of expertise are Juvenile Primary Osteoporosis, Emphysema, Lung Metastases, and Maturity Onset Diabetes of the Young.
Swedish Bone Health & Osteoporosis - Cherry Hill
Dr. Christopher R Shuhart is a Family Practice Specialist in Seattle, Washington. He graduated with honors from Dartmouth Medical School in 1987. Having more than 31 years of diverse experiences, especially in FAMILY PRACTICE, Dr. Christopher R Shuhart affiliates with many hospitals including Swedish Issaquah, Swedish Medical Center, Swedish Edmonds Hospital, Swedish Medical Center / Cherry Hill, St Joseph Medical Center, and cooperates with other doctors and specialists in medical group Swedish Health Services. Dr. Shuhart is rated as a Distinguished provider by MediFind in the treatment of Juvenile Primary Osteoporosis. His top areas of expertise are Osteoporosis, Postmenopausal Osteoporosis, Juvenile Primary Osteoporosis, and Melorheostosis.
Candelas Clinic - Diabetes & Endocrinology & Education
Dr. Stanciu was born and raised in Bucharest, Romania, where she earned her Doctor of Medicine from Carol Davila University. She continued her medical training with an internship in general surgery and a general medicine residency in Bucharest, Romania. Dr. Stanciu moved to the United States in 1997 to complete an Internal Medicine Residency at Cook County Hospital in Chicago. She then completed an Endocrinology Fellowship at Loyola University in Maywood, Illinois.Dr. Stanciu is board-certified in endocrinology, diabetes, and metabolism, and internal medicine. She has expertise in parathyroid, osteoporosis, and other metabolic bone disorders (including rare bone disorders).Dr. Stanciu believes in engaging patients in learning about their disease and available treatment options to achieve the best possible outcomes. She aims to make patients comfortable with their treatment decisions, knowledgeable about the disease process, and encourage them to actively participate in their healing by promoting a healthy and active lifestyle.“I am thorough in my evaluation so I can understand the root cause of the disease, find the appropriate treatment option, and explain to the patient in easy-to-understand language. I love to see the patient getting back to an active lifestyle.”When she is not working, Dr. Stanciu enjoys the beautiful weather and mountains of Colorado, where she can be found hiking and camping in the summer and skiing in the winter. She has two daughters, one granddaughter, and three grandsons.Dr. Stanciu is a 5280 Magazine Top Doctor for 2020, 2021, 2023, and 2024. Dr. Stanciu is rated as an Advanced provider by MediFind in the treatment of Juvenile Primary Osteoporosis. Her top areas of expertise are Osteoporosis, Postmenopausal Osteoporosis, Hyperparathyroidism, and Familial Isolated Hyperparathyroidism.
Published Date: January 01, 2013
Published By: National Institutes of Health