Fecal Microbiota Transplantation (FMT CAPSULE DE, FMPCapDE, MTP-CP101) in Kidney Stone Patients (FMT IND STUDY)
The purpose of this study is to measure the impact of Microbial Transplant Therapy (MTT) on 24-hour urine parameters in recurrent hypercalciuric and hyperoxaluric kidney stone formers.
• Women and men age greater than or equal to 18 and less than 70
• Recent medical history of USD with greater than or equal to 50% calcium-oxalate stones. All patients will have urinary stone disease confirmed by stone analysis. The study will include patients with either stones extracted by urological intervention or spontaneously passed and collected stones.
• 24-hour urinary calcium concentration greater than 225 mg/day or urinary oxalate greater than 40 mg/day
• Able to give informed consent.
• Willing to undergo telephone follow-up to assess for safety and adverse events
• Willing and able to participate in the study requirements, including study visits, 24-hour urine collection and serial stool collection
• Not actively participating in another interventional USD clinical trial
• Estimated Glomerular Filtration Rate (eGFR) greater than or equal to 60.