Kidney StonesSymptoms, Doctors, Treatments, Advances & More
Learn About Kidney Stones
Kidney stones (also called renal stones or urinary stones) are small, hard deposits that form in one or both kidneys; the stones are made up of minerals or other compounds found in urine. Kidney stones vary in size, shape, and color. To be cleared from the body (or "passed"), the stones need to travel through ducts that carry urine from the kidneys to the bladder (ureters) and be excreted. Depending on their size, kidney stones generally take days to weeks to pass out of the body.
Genetic changes can increase the risk of developing kidney stones, often acting in combination with a variety of environmental and lifestyle factors. Most genes involved in the condition are important for transmitting chemical signals from outside cells to inside cells or transporting materials in and out of cells. These processes help regulate the levels of various materials within cells, including the minerals and compounds that make up kidney stones. Changes in these genes can alter the levels of these materials in cells, leading to an imbalance of minerals and compounds in urine. As a result, the likelihood of stone formation increases.
In the United States, 9 percent of women and 19 percent of men develop kidney stones in their lifetime. Caucasians are more likely to develop kidney stones than African Americans.
The inheritance pattern of kidney stones is unclear. Overall, the risk of developing this condition is greater for individuals who have a close relative (such as a parent or sibling) with the condition as compared to the general public.
Duke Urology Clinic - Clinic 1G
I am a urologist who specializes in the medical and surgical management of kidney stones. My practice focuses on comprehensive kidney stone management. I perform a high volume of kidney stone surgeries, including cases with complex anatomy or large kidney stone burden. In addition, I perform evaluations to determine the cause of stones and then provide specific recommendations to prevent future stones. During our visit, I look forward to learning about you and obtaining a thorough history of your past experiences with kidney stones. After we review your laboratory results and imaging, we will discuss the best options to treat your current kidney stones and strategies to prevent them in the future. Dr. Antonelli is rated as an Elite provider by MediFind in the treatment of Kidney Stones. She is also highly rated in 18 other conditions, according to our data. Her clinical expertise encompasses Kidney Stones, Boils, Carbuncle, Ureteroscopy, and Lithotripsy. Dr. Antonelli is board certified in American Board Of Urology, Urology.
Duke Ambulatory Surgery Center
My clinical interests include the minimally invasive management of urinary tract stones, including shock wave lithotripsy, percutaneous, and ureteroscopic stone removal. I completed my training at the University of North Carolina in 1983 and was an American Urological Association Scholar (1983-1985) in the Division of Mineral Metabolism at the University of Texas Southwestern Medical Center, Dallas. In 1993, I returned to North Carolina as professor of urological surgery and director of the Duke Comprehensive Kidney Stone Center. Dr. Preminger is rated as an Elite provider by MediFind in the treatment of Kidney Stones. He is also highly rated in 19 other conditions, according to our data. His clinical expertise encompasses Kidney Stones, Urinary Tract Infection (UTI), Boils, Lithotripsy, and Ureteroscopy. Dr. Preminger is board certified in American Board Of Urology, Urology.
Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
Dr. Brian Matlaga is a Professor of Urology at Johns Hopkins University School of Medicine and also is the Director of the Stephens Center for Stone Disease as well as the Executive Vice Chair of the James Buchanan Brady Urological Institute. Dr. Matlaga is an internationally recognized expert in the medical and surgical management of patients with urinary stone disease. A frequent contributor to the medical press, with over 180 peer-reviewed publications, Dr. Matlaga’s research has received national and international awards. Dr. Matlaga sits on numerous editorial boards as well as advisory committees and guidelines panels for the American Urological Association, the American Board of Urology, the Endourological Society, and the National Institutes of Health, amongst others. Dr. Matlaga serves as Executive Medical Director of Clinical Affairs for Johns Hopkins Medicine International, the arm of Johns Hopkins Medicine that manages its global presence. In this capacity, he delivers clinical care as well as project leadership across the globe. Dr. Matlaga is rated as an Elite provider by MediFind in the treatment of Kidney Stones. He is also highly rated in 17 other conditions, according to our data. His clinical expertise encompasses Kidney Stones, Bladder Stones, Boils, Ureteroscopy, and Lithotripsy. Dr. Matlaga is board certified in American Board Of Urology.
Summary: The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g., transurethral or percutaneous access routes) or benign prostatic hyperplasia (BPH) treatment.
Summary: This study will attempt to identify the specific gene (coded in the DNA) and changes (mutations) within that gene that are the cause of monogenic kidney stone disease. This study will help researchers determine the characteristics of the stone disease associated with specific genes and mutations. This information may help develop more effective treatments for monogenic kidney stone diseases.
Published Date: January 01, 2019
Published By: National Institutes of Health