Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
Status: Recruiting
Location: See location...
Intervention Type: Drug, Dietary supplement
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 99
Healthy Volunteers: f
View:
• \- Calcium Phosphate stone formers
Locations
United States
Texas
UT Southwestern Medical Center
RECRUITING
Dallas
Contact Information
Primary
NAIM M MAALOUF, MD
naim.maalouf@utsouthwestern.edu
214/648-2954
Backup
Miranda King
Miranda.King@utsouthwestern.edu
2146482117
Time Frame
Start Date: 2023-12-13
Estimated Completion Date: 2028-08-31
Participants
Target number of participants: 25
Treatments
Active_comparator: Potassium Citrate (Urocit®-K)
Potassium Citrate KCit 10 mEq 2 tabs, twice daily and Placebo 1 tab, twice daily Total Daily Dose: Citrate 40 mEq/d
Experimental: Super CitriMax; OHCit-standard dose
Super CitriMax 7 mEq 3 tabs, twice daily Total Daily Dose: OHCit 42 mEq/d
Experimental: Super CitriMax; OHCit-low dose
Super CitriMax 7 mEq 2 tabs, twice daily And Placebo 1 tab, twice daily Total Daily Dose: OHCit 28 mEq/d
Placebo_comparator: Placebo
Placebo 3 tablets twice daily Total Daily Dose: None
Related Therapeutic Areas
Sponsors
Leads: University of Texas Southwestern Medical Center