Lactate Dehydrogenase Deficiency Latest Advances

Find the Latest Research About Lactate Dehydrogenase Deficiency

Last Updated: 02/24/2026

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Found 141 publications

Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1.

Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1.

Journal: Journal of medicinal chemistry
Published: January 02, 2026

Protein phosphatase 2A orchestrates hematopoietic fate determination via modulation of lactate metabolism.

Protein phosphatase 2A orchestrates hematopoietic fate determination via modulation of lactate metabolism.

Journal: Haematologica
Published: August 11, 2025

Phospholysine phosphohistidine inorganic pyrophosphate phosphatase suppresses glycolysis and proliferation of pulmonary artery smooth muscle cells in hypoxic pulmonary hypertension via inhibition of lactate dehydrogenase A.

Phospholysine phosphohistidine inorganic pyrophosphate phosphatase suppresses glycolysis and proliferation of pulmonary artery smooth muscle cells in hypoxic pulmonary hypertension via inhibition of lactate dehydrogenase A.

Journal: European journal of pharmacology
Published: June 06, 2025

Multi-omics analyses identify mannose phosphate isomerase-centered hypoxia-induced angiogenesis signature in colorectal cancer.

Multi-omics analyses identify mannose phosphate isomerase-centered hypoxia-induced angiogenesis signature in colorectal cancer.

Journal: Journal of translational medicine
Published: June 03, 2025

Glycogenosis type XI, a rare association between muscle and skin manifestations - the contribution of proteomics for the understanding of the underlying myopathology.

Glycogenosis type XI, a rare association between muscle and skin manifestations - the contribution of proteomics for the understanding of the underlying myopathology.

Journal: Journal of neuromuscular diseases
Published: March 04, 2025

LDHA-Mediated H3K18 Lactylation Promotes the Glycolysis in Non-Small Cell Lung Cancer Through Targeting PTEN.

LDHA-Mediated H3K18 Lactylation Promotes the Glycolysis in Non-Small Cell Lung Cancer Through Targeting PTEN.

Journal: Biochemical genetics
Published: December 19, 2024

GPX4: A Key Regulator of Mitochondrial Function and Glycolysis in Pulmonary Artery Smooth Muscle Cells.

GPX4: A Key Regulator of Mitochondrial Function and Glycolysis in Pulmonary Artery Smooth Muscle Cells.

Journal: Journal of cardiovascular pharmacology
Published: December 18, 2024

SPP1+ macrophages polarized by lactate confer the progression of hypoxic adaptive tumor cells in brain.

SPP1+ macrophages polarized by lactate confer the progression of hypoxic adaptive tumor cells in brain.

Journal: Neuro-oncology
Published: December 13, 2024

Lactate dehydrogenase B deficiency-dependent hyperlactatemia coordinates with necroptosis to worsen septic liver and kidney injuries.

Lactate dehydrogenase B deficiency-dependent hyperlactatemia coordinates with necroptosis to worsen septic liver and kidney injuries.

Journal: Biochemical and biophysical research communications
Published: December 11, 2024

Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection.

Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection.

Journal: Nature communications
Published: November 11, 2024

Use of PopPK and E-R Analyses toward Explaining Causal Link Between ADAMTS13 in Recombinant vs. Plasma-Based Therapies and Clinical Effects in cTTP.

Use of PopPK and E-R Analyses toward Explaining Causal Link Between ADAMTS13 in Recombinant vs. Plasma-Based Therapies and Clinical Effects in cTTP.

Journal: Clinical pharmacology and therapeutics
Published: November 05, 2024

Lactate dehydrogenase A (LDHA)-mediated lactate generation promotes pulmonary vascular remodeling in pulmonary hypertension.

Lactate dehydrogenase A (LDHA)-mediated lactate generation promotes pulmonary vascular remodeling in pulmonary hypertension.

Journal: Journal of translational medicine
Published: May 28, 2024
Showing 1-12 of 141

Last Updated: 02/24/2026