Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both metformin and dapagliflozin, another diabetes drug. The goal is to find clinical or laboratory signs that could help doctors quickly recognize a dapagliflozin overdose in this context, which could improve treatment and patient outcomes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:
• Adults aged 18 years or older
• Admission to an intensive care unit (ICU) due to acute drug poisoning
• Documented exposure to either:
• Metformin alone
• Metformin in combination with dapagliflozin
Locations
Other Locations
France
Centre Hospitalier de Saint-Denis
RECRUITING
Saint-denis
Time Frame
Start Date: 2025-04-11
Estimated Completion Date: 2026-04-11
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier de Saint-Denis