Landau-Kleffner Syndrome
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Landau-Kleffner Syndrome Overview

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Learn About Landau-Kleffner Syndrome

What is the definition of Landau-Kleffner Syndrome?
Landau-Kleffner syndrome (LKS) is a rare neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and recurrent seizures (epilepsy). Males are more often affected by LKS than females. In about 20% of people with LKS, genetic changes (changes) in the GRIN2A gene have been identified. The syndrome is inherited in an autosomal dominant manner. In other cases, the syndrome may be caused by changes to other unidentified genes. LKS is diagnosed when a doctor sees clinical features that are consistent with the syndrome such as a loss of speech and an electroencephalogram (EEG) that shows specific kinds of seizure activity. Genetic testing can be used to confirm if there is a genetic change in GRIN2A, but this testing is not done routinely.
What are the alternative names for Landau-Kleffner Syndrome?
  • Landau-Kleffner syndrome
  • Acquired aphasia with convulsive disorder
  • Acquired epileptic aphasia
  • Acquired epileptiform aphasia
  • LKS
Who are the top Landau-Kleffner Syndrome Local Doctors?
Advanced in Landau-Kleffner Syndrome
Advanced in Landau-Kleffner Syndrome
Referral may be required

Pottstown Hospital

1600 East High Street, 
Pottstown, PA 
610-327-7000
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Ameer Alwafai is a Neurologist practicing medicine in Pottstown, Pennsylvania. Dr. Alwafai is rated as an Advanced provider by MediFind in the treatment of Landau-Kleffner Syndrome. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Stroke, Cerebral Arteriovenous Malformation, Landau-Kleffner Syndrome, and Transient Ischemic Attack (TIA). Dr. Alwafai is board certified in American Board Of Psychiatry And Neurology.

Advanced in Landau-Kleffner Syndrome
Dr. Robert J. Pearlstein
Geriatrics | Internal Medicine
Advanced in Landau-Kleffner Syndrome
Dr. Robert J. Pearlstein
Geriatrics | Internal Medicine
Referral may be required

Suburban Geriatrics Inc

2901 Jolly Road, 
Plymouth Meeting, PA 
610-272-8221
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Robert Pearlstein is a primary care provider, practicing in Geriatrics and Internal Medicine in Plymouth Meeting, Pennsylvania. Dr. Pearlstein is rated as an Advanced provider by MediFind in the treatment of Landau-Kleffner Syndrome. He is also highly rated in 180 other conditions, according to our data. His clinical expertise encompasses Dementia, Alzheimer's Disease, Painful Swallowing, Gastrostomy, and Endoscopy. Dr. Pearlstein is board certified in  .

 
 
 
 
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Experienced in Landau-Kleffner Syndrome
Experienced in Landau-Kleffner Syndrome
Referral may be required

Reading Hospital Neurology Suite 3020

301 S 7th Ave, Ste 3020, 
West Reading, PA 
484-628-4656
Languages Spoken:
English, Gujarati , Hindi, Punjabi
See accepted insurances
Offers Telehealth

Jasdeep Khurana is a Neurologist practicing medicine in West Reading, Pennsylvania. Dr. Khurana is rated as an Experienced provider by MediFind in the treatment of Landau-Kleffner Syndrome. She is also highly rated in 17 other conditions, according to our data. Her clinical expertise encompasses Seizures, Partial Familial Epilepsy, Memory Loss, and Partial Seizure. Dr. Khurana is board certified in American Board Of Psychiatry And Neurology.

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What are the latest Landau-Kleffner Syndrome Clinical Trials?
Music and Cognitive Deficits in Self-Limited Epilepsy with Centrotemporal Spikes
Music and Cognitive Deficits in Self-Limited Epilepsy with Centrotemporal Spikes
Enrollment Status: Recruiting
Publish Date: December 09, 2024
Intervention Type: Other

Summary: Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years. SeLECTS is associated in 15 to 30% of patients with specific cognitive deficits, including in particular disorders in language, visuo-spatial memory, declarative memory, and attention. SeLECTS has the potential to evolve into Landau-Kleffner syndrome, th...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center