Landau-Kleffner Syndrome Overview

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Learn About Landau-Kleffner Syndrome

What is the definition of Landau-Kleffner Syndrome?
Landau-Kleffner syndrome (LKS) is a rare neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and recurrent seizures (epilepsy). Males are more often affected by LKS than females. In about 20% of people with LKS, genetic changes (changes) in the GRIN2A gene have been identified. The syndrome is inherited in an autosomal dominant manner. In other cases, the syndrome may be caused by changes to other unidentified genes. LKS is diagnosed when a doctor sees clinical features that are consistent with the syndrome such as a loss of speech and an electroencephalogram (EEG) that shows specific kinds of seizure activity. Genetic testing can be used to confirm if there is a genetic change in GRIN2A, but this testing is not done routinely.
What are the alternative names for Landau-Kleffner Syndrome?
  • Landau-Kleffner syndrome
  • Acquired aphasia with convulsive disorder
  • Acquired epileptic aphasia
  • Acquired epileptiform aphasia
  • LKS
Who are the top Landau-Kleffner Syndrome Local Doctors?
Elite in Landau-Kleffner Syndrome
Patrick Van Bogaert
Elite in Landau-Kleffner Syndrome
Patrick Van Bogaert
808, Lennik Street, 
Brussels, BRU, BE 

Patrick Van Bogaert practices in Brussels, Belgium. Mr. Van Bogaert is rated as an Elite expert by MediFind in the treatment of Landau-Kleffner Syndrome. His top areas of expertise are Landau-Kleffner Syndrome, Epilepsy, Myoclonic Epilepsy, and West Syndrome.

Distinguished in Landau-Kleffner Syndrome
Dr. Heather R. Mckee
Neurology
Distinguished in Landau-Kleffner Syndrome
Dr. Heather R. Mckee
Neurology

University Of Cincinnati Physicians Company LLC

3113 Bellevue Ave, 
Cincinnati, OH 
513-475-8000
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Heather Mckee is a Neurologist in Cincinnati, Ohio. Dr. Mckee is rated as a Distinguished provider by MediFind in the treatment of Landau-Kleffner Syndrome. Her top areas of expertise are Memory Loss, Seizures, Landau-Kleffner Syndrome, Epilepsy in Children, and Gastrostomy. Dr. Mckee is currently accepting new patients.

 
 
 
 
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Distinguished in Landau-Kleffner Syndrome
Dr. David M. Ficker
Neurology
Distinguished in Landau-Kleffner Syndrome
Dr. David M. Ficker
Neurology

University Of Cincinnati Physicians Company LLC

222 Piedmont Ave, 
Cincinnati, OH 
513-475-7855
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

David Ficker is a Neurologist in Cincinnati, Ohio. Dr. Ficker is rated as a Distinguished provider by MediFind in the treatment of Landau-Kleffner Syndrome. His top areas of expertise are Seizures, Memory Loss, Dravet Syndrome, Landau-Kleffner Syndrome, and Gastrostomy. Dr. Ficker is currently accepting new patients.

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What are the latest Landau-Kleffner Syndrome Clinical Trials?
Music and Cognitive Deficits in Self-Limited Epilepsy with Centrotemporal Spikes
Music and Cognitive Deficits in Self-Limited Epilepsy with Centrotemporal Spikes
Enrollment Status: Recruiting
Publish Date: December 09, 2024
Intervention Type: Other

Summary: Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years. SeLECTS is associated in 15 to 30% of patients with specific cognitive deficits, including in particular disorders in language, visuo-spatial memory, declarative memory, and attention. SeLECTS has the potential to evolve into Landau-Kleffner syndrome, th...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center