Lassa Fever
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Lassa Fever Overview

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Learn About Lassa Fever

What is the definition of Lassa Fever?
Lassa fever is an acute viral, hemorrhagic (bleeding) disease mainly transmitted to humans by rats and/or food or household items contaminated with rodent urine or feces. Human-to-human transmission of Lassa fever can also occur. Lassa fever is endemic (common) in areas of West Africa.
What are the symptoms of Lassa Fever?
Most individuals (80%) who are infected with the Lassa virus do not have any symptoms or only mild symptoms. Symptoms of Lassa fever begin 1-3 weeks after infection. Mild symptoms of Lassa fever may include low fever, headache, sore throat, cough, weakness, muscle pain, and malaise. Symptoms of more severe cases of Lassa fever may include facial swelling; hair loss; gait disorder; hearing loss; encephalitis (brain inflammation); nausea and vomiting; diarrhea; fluid in the lungs; respiratory distress; tremors; chest, back, or abdominal pain; miscarriage; hemorrhaging in the eyes, nose, gums, or gastrointestinal tract; low blood pressure; shock; seizures; coma; multi-organ failure; and death. The most common complication of Lassa fever is either temporary or permanent deafness.
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What are the current treatments for Lassa Fever?
Treatment for Lassa fever includes early supportive care and symptomatic treatment with adequate hydration, oxygen, blood pressure maintenance, and the antiviral drug, Ribavirin.
Who are the top Lassa Fever Local Doctors?
Elite in Lassa Fever
Danny A. Asogun
Elite in Lassa Fever
Danny A. Asogun
Km. 87, Benin/Auchi Road, 
Irrua, ED, NG 

Danny Asogun practices practicing medicine in Irrua, Nigeria. Mr. Asogun is rated as an Elite expert by MediFind in the treatment of Lassa Fever. He is also highly rated in 3 other conditions, according to our data. His clinical expertise encompasses Lassa Fever, Viral Hemorrhagic Fever, Monkeypox, and Ebola Virus Disease.

Elite in Lassa Fever
Donald S. Grant
Elite in Lassa Fever
Donald S. Grant
New England Ville, 
Freetown, W, SL 

Donald Grant practices practicing medicine in Freetown, Sierra Leone. Mr. Grant is rated as an Elite expert by MediFind in the treatment of Lassa Fever. He is also highly rated in 3 other conditions, according to our data. His clinical expertise encompasses Lassa Fever, Viral Hemorrhagic Fever, Ebola Virus Disease, Hearing Loss, and Cataract Removal.

 
 
 
 
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Elite in Lassa Fever
George O. Akpede
Elite in Lassa Fever
George O. Akpede
Ekpoma, ED, NG 

George Akpede practices practicing medicine in Ekpoma, Nigeria. Mr. Akpede is rated as an Elite expert by MediFind in the treatment of Lassa Fever. He is also highly rated in 2 other conditions, according to our data. His clinical expertise encompasses Lassa Fever, Viral Hemorrhagic Fever, Meningitis, and Bacterial Meningitis.

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What are the latest Lassa Fever Clinical Trials?
A Phase 2 Study to Evaluate Safety, Tolerability, And Virologic Efficacy of ARN-75039 For the Treatment of Lassa Fever in West Africa
A Phase 2 Study to Evaluate Safety, Tolerability, And Virologic Efficacy of ARN-75039 For the Treatment of Lassa Fever in West Africa
Enrollment Status: Recruiting
Publish Date: March 11, 2026
Intervention Type: Drug
Study Phase: Phase 2

Summary: This multicenter, randomized, open-label Phase 2 clinical trial evaluates the safety, tolerability, and virologic efficacy of ARN-75039, a novel oral antiviral, for treating Lassa fever in hospitalized adults in West Africa. The study is conducted within the INTEGRATE platform and compares two oral dose regimens of ARN-75039 (100 mg BID and 50 mg BID) with intravenous ribavirin, the locally mandat...

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Efficacy, Tolerability and Safety of New or Repurposed Drugs Against Lassa Fever in West African Countries
Efficacy, Tolerability and Safety of New or Repurposed Drugs Against Lassa Fever in West African Countries
Enrollment Status: Recruiting
Publish Date: February 04, 2026
Intervention Type: Drug
Study Phase: Phase 2/Phase 3

Summary: Lassa fever (LF) is a viral haemorrhagic fever responsible of 5000 deaths per year in West Africa, with in-hospital mortality at 12%. Transmission to humans occurs mainly via direct or indirect exposure to excreta from the rodent reservoir, mainly made up of Mastomys natalensis . Less frequently, LASV may also be transmitted from human to human and cause nosocomial outbreaks. Ribavirin is the only...

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