Late-Onset Retinal Degeneration
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Learn About Late-Onset Retinal Degeneration

What is the definition of Late-Onset Retinal Degeneration?
Late-onset retinal degeneration is an inherited retinal dystrophy characterized by delayed dark adaptation and nyctalopia and drusen deposits presenting in adulthood, followed by cone and rod degeneration that presents in the sixth decade of life, which leads to central vision loss. Anterior segment features such as peripupillary iris transillumination defects and abnormally long anterior zonular insertions are also observed. Choroidal neovascularization and glaucoma may occur in the late stages of the disease.
What are the alternative names for Late-Onset Retinal Degeneration?
  • Late-onset retinal degeneration
  • Autosomal dominant late-onset retinal degeneration
  • LORD
  • Pigmentary retinopathy
  • Retinal degeneration, late-onset, autosomal dominant
Who are the top Late-Onset Retinal Degeneration Local Doctors?
Peter Kaiser
Elite in Late-Onset Retinal Degeneration
Ophthalmology
Elite in Late-Onset Retinal Degeneration
Ophthalmology

Cleveland Clinic Main Campus

2022 East 105th Street, 
Cleveland, OH 
Experience:
38+ years
Languages Spoken:
English

Peter Kaiser is an Ophthalmologist in Cleveland, Ohio. Dr. Kaiser has been practicing medicine for over 38 years and is rated as an Elite provider by MediFind in the treatment of Late-Onset Retinal Degeneration. His top areas of expertise are Age-Related Macular Degeneration (ARMD), Late-Onset Retinal Degeneration, Geographic Atrophy, Vitrectomy, and Osteotomy.

Glenn J. Jaffe
Elite in Late-Onset Retinal Degeneration
Ophthalmology | General Surgery
Elite in Late-Onset Retinal Degeneration
Ophthalmology | General Surgery

Duke Eye Center

2351 Erwin Rd, 
Durham, NC 
Experience:
39+ years
Languages Spoken:
English
Offers Telehealth

I’m a retina specialist who takes care of patients who have problems with the back of the eye. When a patient comes to see me, I like getting to know them and their history, so that I can tailor their treatment. My patients come from a variety of different backgrounds, so I find that I often learn as much from them as they do from me. Everybody has a different story and I very much like to learn about the patients to whom I provide care. Duke is a great place at which to work and from which to seek treatment because it’s a very collaborative institution. Everyone works together to do what’s best for the patient. Outside of work, I like to spend as much time as possible with my family. I also enjoy cooking, playing sports and watching sports. Dr. Jaffe is rated as an Elite provider by MediFind in the treatment of Late-Onset Retinal Degeneration. His top areas of expertise are Age-Related Macular Degeneration (ARMD), Late-Onset Retinal Degeneration, Geographic Atrophy, Vitrectomy, and Cataract Removal.

 
 
 
 
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Peter A. Campochiaro
Elite in Late-Onset Retinal Degeneration
Elite in Late-Onset Retinal Degeneration

The Johns Hopkins Hospital

1800 Orleans Street, Maumenee Lobby, Maumenee Lobby, 
Baltimore, MD 
Languages Spoken:
English

Peter A. Campochiaro, M.D. is the George S. and Dolores Doré Eccles Professor of Ophthalmology and Neuroscience at the Wilmer Eye Institute, Johns Hopkins University School of Medicine. He is a clinician-scientist who directs a research laboratory and conducts clinical trials. His laboratory research is directed at understanding the pathogenesis of ocular neovascularization and excessive retinal vascular permeability, and the mechanism of cone cell death in inherited retinal degenerations. He helped to determine the importance of vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1, and Tie2 in retinal and choroidal vascular diseases. The clinical trial group under Dr. Campochairo provided the first demonstration of the benefits of suppression of VEGF in diabetic macular edema and retinal vein occlusion. He has developed strategies for sustained suppression of VEGF that are currently being tested in clinical trials. Dr. Campochiaro trained at the University of Notre Dame, Johns Hopkins School of Medicine, and the University of Virginia. He did a vitreoretinal fellowship and research fellowships at Johns Hopkins and joined the faculty of the University of Virginia in 1984. He became professor of Ophthalmology and Neuroscience at the Wilmer Eye Institute, Johns Hopkins in 1991. Dr. Campochiaro is rated as an Elite provider by MediFind in the treatment of Late-Onset Retinal Degeneration. His top areas of expertise are Retinal Vein Occlusion, Late-Onset Retinal Degeneration, Age-Related Macular Degeneration (ARMD), Trabeculectomy, and Vitrectomy.

What are the latest Late-Onset Retinal Degeneration Clinical Trials?
Intra Ocular Pressure Monitoring After Intravitreal Injection of Aflibercept 8mg/0.07mL

Summary: In just a few years, intravitreal injections have become a standard method of administration for certain retinal deseases (age-related macular degeneration \[AMD\], diabetic edematous maculopathy or retinal vein occlusion \[RVO\]). Thus, vascular endothelial growth factor (anti-VEGF) inhibitors are injected repetitively, every 4 to 6 weeks, in some patients in order to treat such pathologies. It i...

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Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of ABBV-6628 in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Summary: Age-related macular degeneration (AMD) is the abnormal growth of new blood vessels in the light-sensitive tissue at the back of the eye called the retina. Geographic Atrophy (GA) is an advanced form of dry AMD. The purpose of this study is to assess the adverse events and how intravitreal ABBV-6628 moves through the body of adult participants with secondary to age-related macular degeneration ABBV...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center